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BioMed Research International
Volume 2015, Article ID 135893, 10 pages
Clinical Study

Effects of Music Aerobic Exercise on Depression and Brain-Derived Neurotrophic Factor Levels in Community Dwelling Women

1Department of Medical Research and Development, Show Chwan Memorial Hospital, Changhua 500, Taiwan
2Department of Nursing, Central Taiwan University of Science & Technology, Taichung 400, Taiwan
3Department of Nursing, Hungkuang University, Taichung 433, Taiwan
4Yin Huo Health Association, Kaohsiung 806, Taiwan
5School of Nursing, National Taichung University of Science & Technology, Taichung 403, Taiwan
6Department of Nursing, Tzu Hui Institute of Technology, Pingtung County 926, Taiwan
7Institute of Clinical Medicine, National Yang Ming University, Taipei 112, Taiwan

Received 22 January 2015; Revised 7 April 2015; Accepted 8 April 2015

Academic Editor: Esteban Martinez

Copyright © 2015 Shu-Hui Yeh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A randomized clinical trial was utilized to compare the improvement of depression and brain-derived neurotrophic factor (BDNF) levels between community women with and without music aerobic exercise (MAE) for 12 weeks. The MAE group involved 47 eligible participants, whereas the comparison group had 59 participants. No significant differences were recorded in the demographic characteristics between the participants in the MAE group and the comparison group. Forty-one participants in the MAE group and 26 in the comparison group completed a pre- and posttest. The MAE group displayed significant improvement in depression scores (p = 0.016), decreased depression symptoms in crying (p = 0.03), appetite (p = 0.006), and fatigue (p = 0.011). The BDNF levels of the participants significantly increased after the 12-week MAE (p = 0.042). The parallel comparison group revealed no significant changes in depression scores or BDNF levels. In summary, the 12-week MAE had a significant impact on the enhancement of BDNF levels and improvement of depression symptoms. Middle-aged community women are encouraged to exercise moderately to improve their depression symptoms and BDNF levels.