A Protective Role of Arecoline Hydrobromide in Experimentally Induced Male Diabetic Rats

Figure 7

Transmission electron micrographs of arecoline treatment in the prostatic cells of the rats. (a) Ultrastructure of the prostate of untreated rats showing ovoid euchromatic nucleus (N) and moderate number of rough endoplasmic reticula (RER). (b) Arecoline treatment led to an abundance of well-organized RER in the epithelial cells of the prostate. (c) Alloxan-induced diabetic prostate with reduced nuclear size (N) and increased degenerated dense core vesicles (DCVs) and RER in the condensed cell cytoplasm. (d) Arecoline treatment of alloxan-induced rats showing enlarged nucleus and abundance of RER. Scale bars: 1 μm (a, b, and c) and 1.5 μm (d).

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