Review Article

The Role of Ovarian Sex Steroids in Metabolic Homeostasis, Obesity, and Postmenopausal Breast Cancer: Molecular Mechanisms and Therapeutic Implications

Figure 1

Diagram linking menopause and alterations in cellular metabolism with obesity and breast cancer. FAS: saturated fatty acid; TCA: tricarboxylic acid cycle; TNFα: tumor necrosis factor α; IL-1: interleukin-1; IL-6, interleukin-6; SHBG: sex hormone binding globulin; E2: estradiol; IGF-1: insulin-like-growth-factor-1.