Genetic Variability of Candida albicans Sap8 Propeptide in Isolates from Different Types of Infection

Figure 1

(a) Schematic representation of SC5314 C. albicans SAP8 gene, showing the repetitive CAVIII region and the Asp (eukaryotic aspartyl protease) motif of the protein. (b) Representation of the Sap8 protein, showing the signal sequence (0 to 25 amino acids), the propeptide (26 to 88 aminoacids, with the microsatellite CAVIII within), and the mature domain (89 to 405 amino acids).

(a)

(b)