Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2015 (2015), Article ID 149573, 8 pages
http://dx.doi.org/10.1155/2015/149573
Research Article

Effects of Adherence to Statin Therapy on Health Care Outcomes and Utilizations in Taiwan: A Population-Based Study

Institute of Health Care Management, National Sun Yat-sen University, 70 Lien-Hai Road, Kaohsiung 804, Taiwan

Received 22 May 2015; Revised 3 August 2015; Accepted 3 August 2015

Academic Editor: Elísio Costa

Copyright © 2015 Ying-Chun Li and Wei-Ling Huang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. S. Benner, R. J. Glynn, H. Mogun, P. J. Neumann, M. C. Weinstein, and J. Avorn, “Long-term persistence in use of statin therapy in elderly patients,” Journal of the American Medical Association, vol. 288, no. 4, pp. 455–461, 2002. View at Publisher · View at Google Scholar · View at Scopus
  2. E. S. Parris, D. B. Lawrence, L. A. Mohn, and L. B. Long, “Adherence to statin therapy and LDL cholesterol goal attainment by patients with diabetes and dyslipidemia,” Diabetes Care, vol. 28, no. 3, pp. 595–599, 2005. View at Publisher · View at Google Scholar · View at Scopus
  3. M. C. Sokol, K. A. McGuigan, R. R. Verbrugge, and R. S. Epstein, “Impact of medication adherence on hospitalization risk and healthcare cost,” Medical Care, vol. 43, no. 6, pp. 521–530, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. A. W. Roberts, G. D. Crisp, D. A. Esserman, M. T. Roth, M. Weinberger, and J. F. Farley, “Patterns of medication adherence and health care utilization among patients with chronic disease who were enrolled in a pharmacy assistance program,” North Carolina Medical Journal, vol. 75, no. 5, pp. 310–318, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. N. H. Miller, “Compliance with treatment regimens in chronic asymptomatic diseases,” The American Journal of Medicine, vol. 102, no. 2, pp. 43–49, 1997. View at Publisher · View at Google Scholar · View at Scopus
  6. E. A. Schlenk, L. E. Burke, and C. Rand, “Behavioral strategies to improve medication-taking compliance,” in Compliance in Healthcare and Research, L. E. Burke and I. S. Ockene, Eds., pp. 57–70, Futura Publishing, Arnonk, NY, USA, 2001. View at Google Scholar
  7. P. M. Ho, C. L. Bryson, and J. S. Rumsfeld, “Medication adherence: its importance in cardiovascular outcomes,” Circulation, vol. 119, no. 23, pp. 3028–3035, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. L. Wei, J. Wang, P. Thompson, S. Wong, A. D. Struthers, and T. M. MacDonald, “Adherence to statin treatment and readmission of patients after myocardial infarction: a six year follow up study,” Heart, vol. 88, no. 3, pp. 229–233, 2002. View at Publisher · View at Google Scholar · View at Scopus
  9. K. A. Kyanko, R. H. Franklin, and S. Y. Angell, “Adherence to chronic disease medications among New York City Medicaid participants,” Journal of Urban Health, vol. 90, no. 2, pp. 323–328, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Krousel-Wood, S. Thomas, P. Muntner, and D. Morisky, “Medication adherence: a key factor in achieving blood pressure control and good clinical outcomes in hypertensive patients,” Current Opinion in Cardiology, vol. 19, no. 4, pp. 357–362, 2004. View at Publisher · View at Google Scholar · View at Scopus
  11. J.-H. Park, Y. Shin, S.-Y. Lee, and S. I. Lee, “Antihypertensive drug medication adherence and its affecting factors in South Korea,” International Journal of Cardiology, vol. 128, no. 3, pp. 392–398, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. S. K. Gandhi, M. M. Jensen, K. M. Fox, L. Smolen, A. G. Olsson, and T. Paulsson, “Cost-effectiveness of rosuvastatin in comparison with generic atorvastatin and simvastatin in a swedish population at high risk of cardiovascular events,” ClinicoEconomics and Outcomes Research, vol. 4, no. 1, pp. 1–11, 2012. View at Google Scholar · View at Scopus
  13. Cholesterol Treatment Trialists' (CTT) Collaborators, “Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins,” The Lancet, vol. 366, no. 9493, pp. 1267–1278, 2005. View at Publisher · View at Google Scholar
  14. D. O. Fedder, C. E. Koro, and G. J. L'Italien, “New National Cholesterol Education Program III guidelines for primary prevention lipid-lowering drug therapy,” Circulation, vol. 105, no. 2, pp. 152–156, 2002. View at Publisher · View at Google Scholar · View at Scopus
  15. H.-S. Kim, Y. Wu, S.-J. Lin et al., “Current status of cholesterol goal attainment after statin therapy among patients with hypercholesterolemia in Asian countries and region: the Return on Expenditure Achieved for Lipid Therapy in Asia (REALITY-Asia) study,” Current Medical Research and Opinion, vol. 24, no. 7, pp. 1951–1963, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. National Health Research Institutes, National Health Insurance Research Database, 2015, http://nhird.nhri.org.tw/en/index.html.
  17. M. J. Lage and M. K. Hassan, “The relationship between antipsychotic medication adherence and patient outcomes among individuals diagnosed with bipolar disorder: a retrospective study,” Annals of General Psychiatry, vol. 8, article 7, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. C.-H. Tang, M. H. Hsieh, S.-T. Hung, I. H. Lee, Y.-J. Lin, and Y. K. Yang, “One-year post-hospital medical costs and relapse rates of bipolar disorder patients in Taiwan: a population-based study,” Bipolar Disorders, vol. 12, no. 8, pp. 859–865, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. M. M. Spence, A. A. Makarem, S. L. Reyes et al., “Evaluation of an outpatient pharmacy clinical services program on adherence and clinical outcomes among patients with diabetes and/or coronary artery disease,” Journal of Managed Care Pharmacy, vol. 20, no. 10, pp. 1036–1045, 2014. View at Google Scholar
  20. R. B. Stewart and G. J. Caranasos, “Medication compliance in the elderly,” Medical Clinics of North America, vol. 73, no. 6, pp. 1551–1563, 1989. View at Google Scholar · View at Scopus
  21. J. J. Vlasnik, S. L. Aliotta, and B. DeLor, “Medication adherence: factors influencing compliance with prescribed medication plans,” Case Manager, vol. 16, no. 2, pp. 47–51, 2005. View at Publisher · View at Google Scholar · View at Scopus
  22. M. Hassan and M. J. Lage, “Risk of rehospitalization among bipolar disorder patients who are nonadherent to antipsychotic therapy after hospital discharge,” American Journal of Health-System Pharmacy, vol. 66, no. 4, pp. 358–365, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. S. E. Andrade, K. H. Kahler, F. Frech, and K. A. Chan, “Methods for evaluation of medication adherence and persistence using automated databases,” Pharmacoepidemiology and Drug Safety, vol. 15, no. 8, pp. 565–574, 2006. View at Publisher · View at Google Scholar · View at Scopus
  24. World Health Organization, Adherence to Long Term Therapies: Evidence for Action, World Health Organization, Geneva, Switzerland, 2003.