The Association between Cerebral White Matter Lesions and Plasma Omega-3 to Omega-6 Polyunsaturated Fatty Acids Ratio to Cognitive Impairment Development
Table 3
Comparative data of Mini-Mental State Examination (MMSE) scores and background diseases between patients with advanced grade (grade ≥ 3 in DSWMH or grade ≥ III in PVH) and those with both no or mild grade in DSWMH and PVH.
Groups
A
B
C
value
WMH
No or mild
Moderate
Advanced
Grades
(0, I and 0, 1)
(II and 2)
(III, IV or 3, 4)
Patients number
74
84
58
Male/female
46/28
45/39
29/29
ns
Age
66.9 ± 5.3
67.5 ± 5.2
70.6 ± 6.3
MMSE scores
29.7 ± 1.0
29.3 ± 1.3
28.4 ± 2.1
EPA/AA
0.56 ± 0.20
0.36 ± 0.18
0.34 ± 0.24
DHA/AA
1.0 ± 0.24
0.79 ± 0.22
0.78 ± 0.24
Hypertension
43/31
60/24
48/10
Dyslipidemia (+/−)
46/28
63/21
37/21
Diabetes (+/−)
7/67
14/70
8/50
Smoking (+/−)
22/52
30/54
23/35
ICA plaque (+/−)
45/29
62/22
48/10
Between groups A and B, between groups A and C, and between groups B and C.
