Research Article

Ameliorative Effect of Zinc Oxide Nanoparticles on Antioxidants and Sperm Characteristics in Streptozotocin-Induced Diabetic Rat Testes

Table 3

Biochemical investigations in experimental rats administered zinc oxide nanoparticles.

ParametersControl DiabeticDiabetic + ZnONPs Diabetic + ZnONPs + insulin

MDA (nmol/g tissue)1.2 ± 0.065.6 ± 0.51.7 ± 0.31.3 ± 0.05
GSH (μmol/g tissue)123 ± 440 ± 2121 ± 8131 ± 4
SOD (μg/g tissue)55.7 ± 3.224 ± 2.647.3 ± 2.556.7 ± 3.5
CAT (μMH2O2 decomposed/g tissue)1043 ± 51223 ± 25943 ± 401110 ± 36
GPx (μM/min/g tissue)166.7 ± 1535.7 ± 5161 ± 7173 ± 12
GRD (unit/g tissue)15.7 ± 22.9 ± 0.913 ± 216.1 ± 0.8
GST (μmol GSHCDNB conjugate/min/mg protein)86 ± 3.526 ± 481 ± 692 ± 2.5

Each point represents the mean ±  from triplicate determinations ( rats per group). Means within the same row carrying different superscripts (a, b, and c) are significant at .