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BioMed Research International
Volume 2015 (2015), Article ID 158097, 7 pages
http://dx.doi.org/10.1155/2015/158097
Research Article

Retrobulbar Hemodynamics and Visual Field Progression in Normal Tension Glaucoma: A Long-Term Follow-Up Study

Department of Ophthalmology, RWTH Aachen University, Pauwelsstraße 30, 52072 Aachen, Germany

Received 27 May 2015; Revised 27 July 2015; Accepted 28 July 2015

Academic Editor: Toru Nakazawa

Copyright © 2015 D. Kuerten et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. W. Evans, A. Harris, M. Garrett, H. S. Chung, and L. Kagemann, “Glaucoma patients demonstrate faulty autoregulation of ocular blood flow during posture change,” British Journal of Ophthalmology, vol. 83, no. 7, pp. 809–813, 1999. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Flammer, I. O. Haefliger, S. Orgül, and T. Resink, “Vascular dysregulation: a principal risk factor for glaucomatous damage?” Journal of Glaucoma, vol. 8, no. 3, pp. 212–219, 1999. View at Google Scholar · View at Scopus
  3. E. Gramer and M. Tausch, “The risk profile of the glaucomatous patient,” Current Opinion in Ophthalmology, vol. 6, no. 2, pp. 78–88, 1995. View at Google Scholar · View at Scopus
  4. H. A. Quigley and E. M. Addicks, “Regional differences in the structure of the lamina cribrosa and their relation to glaucomatous optic nerve damage,” Archives of Ophthalmology, vol. 99, no. 1, pp. 137–143, 1981. View at Publisher · View at Google Scholar · View at Scopus
  5. S. Resnikoff, D. Pascolini, D. Etya'ale et al., “Global data on visual impairment in the year 2002,” Bulletin of the World Health Organization, vol. 82, no. 11, pp. 844–851, 2004. View at Google Scholar
  6. H. A. Quigley and A. T. Broman, “The number of people with glaucoma worldwide in 2010 and 2020,” British Journal of Ophthalmology, vol. 90, no. 3, pp. 262–267, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. I. Stalmans, B. Siesky, T. Zeyen, S. Fieuws, and A. Harris, “Reproducibility of color Doppler imaging,” Graefe's Archive for Clinical and Experimental Ophthalmology, vol. 247, no. 11, pp. 1531–1538, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. I. Stalmans, E. Vandewalle, D. R. Anderson et al., “Use of colour Doppler imaging in ocular blood flow research,” Acta Ophthalmologica, vol. 89, no. 8, pp. e609–e630, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. S. J. A. Rankin, “Color Doppler imaging of the retrobulbar circulation in glaucoma,” Survey of Ophthalmology, vol. 43, supplement 1, pp. S176–S182, 1999. View at Publisher · View at Google Scholar · View at Scopus
  10. J. R. Trible, R. C. Sergott, G. L. Spaeth et al., “Trabeculectomy is associated with retrobulbar hemodynamic changes: a color Doppler analysis,” Ophthalmology, vol. 101, no. 2, pp. 340–351, 1994. View at Publisher · View at Google Scholar · View at Scopus
  11. Z. Butt, C. O'Brien, G. McKillop, P. Aspinall, and P. Allan, “Color Doppler imaging in untreated high- and normal-pressure open-angle glaucoma,” Investigative Ophthalmology & Visual Science, vol. 38, no. 3, pp. 690–696, 1997. View at Google Scholar · View at Scopus
  12. N. Plange, M. Kaup, A. Weber, A. Harris, K. O. Arend, and A. Remky, “Performance of colour Doppler imaging discriminating normal tension glaucoma from healthy eyes,” Eye, vol. 23, no. 1, pp. 164–170, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. N. Plange, A. Remky, and O. Arend, “Colour Doppler imaging and fluorescein filling defects of the optic disc in normal tension glaucoma,” British Journal of Ophthalmology, vol. 87, no. 6, pp. 731–736, 2003. View at Publisher · View at Google Scholar · View at Scopus
  14. N. Plange, M. Kaup, O. Arend, and A. Remky, “Asymmetric visual field loss and retrobulbar haemodynamics in primary open-angle glaucoma,” Graefe's Archive for Clinical and Experimental Ophthalmology, vol. 244, no. 8, pp. 978–983, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. S. J. Rankin, S. M. Drance, A. R. Buckley, and B. E. Walman, “Visual field correlations with color Doppler studies in open angle glaucoma,” Journal of Glaucoma, vol. 5, no. 1, pp. 15–21, 1996. View at Google Scholar
  16. C. J. Liu, H.-J. Chiou, S.-C. Chiang, J. C. Chou, Y.-H. Chou, and J.-H. Liu, “Variations in ocular hemodynamics in patients with early and late glaucoma,” Acta Ophthalmologica Scandinavica, vol. 77, no. 6, pp. 658–662, 1999. View at Publisher · View at Google Scholar · View at Scopus
  17. J. Schumann, S. Orgül, K. Gugleta, B. Dubler, and J. Flammer, “Interocular difference in progression of glaucoma correlates with interocular differences in retrobulbar circulation,” American Journal of Ophthalmology, vol. 129, no. 6, pp. 728–733, 2000. View at Publisher · View at Google Scholar · View at Scopus
  18. D. Gherghel, S. Orgül, K. Gugleta, M. Gekkieva, and J. Flammer, “Relationship between ocular perfusion pressure and retrobulbar blood flow in patients with glaucoma with progressive damage,” American Journal of Ophthalmology, vol. 130, no. 5, pp. 597–605, 2000. View at Publisher · View at Google Scholar · View at Scopus
  19. A. Martínez and M. Sánchez, “Predictive value of colour Doppler imaging in a prospective study of visual field progression in primary open-angle glaucoma,” Acta Ophthalmologica Scandinavica, vol. 83, no. 6, pp. 716–722, 2005. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Satilmis, S. Orgül, B. Doubler, and J. Flammer, “Rate of progression of glaucoma correlates with retrobulbar circulation and intraocular pressure,” American Journal of Ophthalmology, vol. 135, no. 5, pp. 664–669, 2003. View at Publisher · View at Google Scholar · View at Scopus
  21. F. Galassi, A. Sodi, F. Ucci, G. Renieri, B. Pieri, and M. Baccini, “Ocular hemodynamics and glaucoma prognosis: a color Doppler imaging study,” Archives of Ophthalmology, vol. 121, no. 12, pp. 1711–1715, 2003. View at Publisher · View at Google Scholar · View at Scopus
  22. P. Calvo, A. Ferreras, V. Polo et al., “Predictive value of retrobulbar blood flow velocities in glaucoma suspects,” Investigative Ophthalmology and Visual Science, vol. 53, no. 7, pp. 3875–3884, 2012. View at Publisher · View at Google Scholar · View at Scopus
  23. O. Zeitz, P. Galambos, L. Wagenfeld et al., “Glaucoma progression is associated with decreased blood flow velocities in the short posterior ciliary artery,” British Journal of Ophthalmology, vol. 90, no. 10, pp. 1245–1248, 2006. View at Publisher · View at Google Scholar · View at Scopus
  24. F. Jimenez-Aragon, E. Garcia-Martin, R. Larrosa-Lopez, J. M. Artigas-Martín, P. Seral-Moral, and L. E. Pablo, “Role of color Doppler imaging in early diagnosis and prediction of progression in glaucoma,” BioMed Research International, vol. 2013, Article ID 871689, 11 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. D. Kuerten, M. Fuest, E. C. Koch, A. Remky, and N. Plange, “Long term effect of trabeculectomy on retrobulbar haemodynamics in glaucoma,” Ophthalmic and Physiological Optics, vol. 35, no. 2, pp. 194–200, 2014. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Kaup, N. Plange, K. O. Arend, and A. Remky, “Retrobulbar haemodynamics in non-arteritic anterior ischaemic optic neuropathy,” British Journal of Ophthalmology, vol. 90, no. 11, pp. 1350–1353, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. N. Plange, M. Kaup, A. Weber, K. O. Arend, and A. Remky, “Retrobulbar haemodynamics and morphometric optic disc analysis in primary open-angle glaucoma,” British Journal of Ophthalmology, vol. 90, no. 12, pp. 1501–1504, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. T. H. Williamson and A. Harris, “Color Doppler ultrasound imaging of the eye and orbit,” Survey of Ophthalmology, vol. 40, no. 4, pp. 255–267, 1996. View at Publisher · View at Google Scholar
  29. A. Harris, T. H. Williamson, B. Martin et al., “Test/retest reproducibility of color Doppler imaging assessment of blood flow velocity in orbital vessels,” Journal of Glaucoma, vol. 4, no. 4, pp. 281–286, 1995. View at Google Scholar
  30. B. Bengtsson and A. Heijl, “A visual field index for calculation of glaucoma rate of progression,” American Journal of Ophthalmology, vol. 145, no. 2, pp. 343–353, 2008. View at Publisher · View at Google Scholar
  31. P. Casas-Llera, G. Rebolleda, F. J. Muñoz-Negrete, F. Arnalich-Montiel, M. Pérez-López, and R. Fernández-Buenaga, “Visual field index rate and event-based glaucoma progression analysis: comparison in a glaucoma population,” British Journal of Ophthalmology, vol. 93, no. 12, pp. 1576–1579, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. V. P. Costa, R. C. Sergott, M. Smith et al., “Color Doppler imaging in glaucoma patients with asymmetric optic cups,” Journal of Glaucoma, vol. 3, supplement 1, pp. S91–S97, 1994. View at Publisher · View at Google Scholar · View at Scopus
  33. Y. Yamazaki and S. M. Drance, “The relationship between progression of visual field defects and retrobulbar circulation in patients with glaucoma,” American Journal of Ophthalmology, vol. 124, no. 3, pp. 287–295, 1997. View at Publisher · View at Google Scholar · View at Scopus
  34. J. Nemeth, R. Kovacs, Z. Harkanyi, K. Knezy, K. Senyi, and I. Marsovszky, “Observer experience improves reproducibility of color Doppler sonography of orbital blood vessels,” Journal of Clinical Ultrasound, vol. 30, no. 6, pp. 332–335, 2002. View at Publisher · View at Google Scholar
  35. G. K. Kouvidis, A. Benos, G. Kyriakopoulou, G. Anastopoulos, and D. Triantafyllou, “Colour Doppler ultrasonography of the ophthalmic artery: flow parameters in normal subjects. The significance of the resistance index,” International Angiology, vol. 19, no. 4, pp. 319–325, 2000. View at Google Scholar · View at Scopus
  36. R. Ehrlich, A. Harris, B. A. Siesky et al., “Repeatability of retrobulbar blood flow velocity measured using color doppler imaging in the indianapolis glaucoma progression study,” Journal of Glaucoma, vol. 20, no. 9, pp. 540–547, 2011. View at Publisher · View at Google Scholar · View at Scopus
  37. A. Heijl, M. C. Leske, B. Bengtsson, L. Hyman, and M. Hussein, “Reduction of intraocular pressure and glaucoma progression: results from the early manifest glaucoma trial,” Archives of Ophthalmology, vol. 120, no. 10, pp. 1268–1279, 2002. View at Publisher · View at Google Scholar · View at Scopus
  38. M. C. Leske, A. Heijl, L. Hyman, B. Bengtsson, L. Dong, and Z. Yang, “Predictors of long-term progression in the early manifest glaucoma trial,” Ophthalmology, vol. 114, no. 11, pp. 1965–1972, 2007. View at Publisher · View at Google Scholar · View at Scopus
  39. Z. Bohdanecka, S. Orgül, A. B. Meyer, C. Prünte, and J. Flammer, “Relationship between blood flow velocities in retrobulbar vessels and laser Doppler flowmetry at the optic disk in glaucoma patients,” Ophthalmologica, vol. 213, no. 3, pp. 145–149, 1999. View at Publisher · View at Google Scholar · View at Scopus
  40. O. Zeitz, S. E. Vilchez, E. T. Matthiessen, G. Richard, and M. Klemm, “Volumetric colour Doppler imaging: a useful tool for the determination of ocular blood flow in glaucoma patients?” Eye, vol. 20, no. 6, pp. 668–673, 2006. View at Publisher · View at Google Scholar · View at Scopus