Research Article

Bone Marrow Pathology Predicts Mortality in Chronic Hemodialysis Patients

Table 4

Bone marrow biopsy findings stratified according to survival status ().

VariableTotal ()Survivors ()Nonsurvivors () value

Cellularity, (%)Hypocellularity40 (51.3)20 (41.7)20 (66.7)0.077
Normocellularity23 (29.5)18 (37.5)5 (16.7)
Hypercellularity15 (19.2)10 (20.8)5 (16.7)

Megakaryocyte distribution, (%)Normal57 (73.1)39 (81.3)18 (60.0)0.001**
Increased6 (7.7)6 (6.3)0 (0)
Decreased13 (16.7)3 (6.3)10 (33.3)
Absence2 (2.6)0 (0)2 (6.7)

Morphology, megakaryocytes, (%)Normal77 (98.7)48 (100.0)29 (96.7)0.385
Dysplasia1 (1.3)0 (0)1 (3.3)

M/E ratio3.5 5.982.62 1.645.12 9.300.154

Myeloid series (%)50.73 17.2853.06 16.2147.08 18.530.140

Blast cells (%)0.90 1.061.02 1.190.70 0.770.213

Promyelocytes (%)2.38 3.162.47 3.712.22 1.870.743

Myelocytes + metamyelocytes (%)18.52 9.8118.08 9.2919.23 10.700.618

Band cell + segmental cell (%)29.58 14.1632.48 14.3824.94 12.700.021*

Morphology, myeloid seriesNormal77 (98.7)48 (100.0)29 (96.7)0.194
Abnormal1 (1.3)0 (0)1 (3.3)

Erythroid series (%)23.99 12.4924.98 11.1122.39 14.480.407

Morphology, erythroid seriesNormal77 (98.7)48 (100.0)29 (96.7)0.328
Dysplasia1 (1.3)0 (0)1 (3.3)

Monohistiocytes (%)1.07 1.231.10 1.321.02 1.140.814

Eosinophils (%)3.41 3.233,91 3.192.60 3.190.085

Plasma cells (%)4.40 10.252.64 2.247.35 16.280.139

Lymphoid cells (%)15.59 11.5612.99 7.7719.74 15.100.029*

Iron store (grade)2.41 1.332.35 1.162.54 1.660.713

*, **.