Research Article
Bone Marrow Pathology Predicts Mortality in Chronic Hemodialysis Patients
Table 4
Bone marrow biopsy findings stratified according to survival status (
).
| Variable | Total () | Survivors () | Nonsurvivors () | value |
| Cellularity, (%) | Hypocellularity | 40 (51.3) | 20 (41.7) | 20 (66.7) | 0.077 | Normocellularity | 23 (29.5) | 18 (37.5) | 5 (16.7) | Hypercellularity | 15 (19.2) | 10 (20.8) | 5 (16.7) |
| Megakaryocyte distribution, (%) | Normal | 57 (73.1) | 39 (81.3) | 18 (60.0) | 0.001** | Increased | 6 (7.7) | 6 (6.3) | 0 (0) | Decreased | 13 (16.7) | 3 (6.3) | 10 (33.3) | Absence | 2 (2.6) | 0 (0) | 2 (6.7) |
| Morphology, megakaryocytes, (%) | Normal | 77 (98.7) | 48 (100.0) | 29 (96.7) | 0.385 | Dysplasia | 1 (1.3) | 0 (0) | 1 (3.3) |
| M/E ratio | 3.5 5.98 | 2.62 1.64 | 5.12 9.30 | 0.154 |
| Myeloid series (%) | 50.73 17.28 | 53.06 16.21 | 47.08 18.53 | 0.140 |
| Blast cells (%) | 0.90 1.06 | 1.02 1.19 | 0.70 0.77 | 0.213 |
| Promyelocytes (%) | 2.38 3.16 | 2.47 3.71 | 2.22 1.87 | 0.743 |
| Myelocytes + metamyelocytes (%) | 18.52 9.81 | 18.08 9.29 | 19.23 10.70 | 0.618 |
| Band cell + segmental cell (%) | 29.58 14.16 | 32.48 14.38 | 24.94 12.70 | 0.021* |
| Morphology, myeloid series | Normal | 77 (98.7) | 48 (100.0) | 29 (96.7) | 0.194 | Abnormal | 1 (1.3) | 0 (0) | 1 (3.3) |
| Erythroid series (%) | 23.99 12.49 | 24.98 11.11 | 22.39 14.48 | 0.407 |
| Morphology, erythroid series | Normal | 77 (98.7) | 48 (100.0) | 29 (96.7) | 0.328 | Dysplasia | 1 (1.3) | 0 (0) | 1 (3.3) |
| Monohistiocytes (%) | 1.07 1.23 | 1.10 1.32 | 1.02 1.14 | 0.814 |
| Eosinophils (%) | 3.41 3.23 | 3,91 3.19 | 2.60 3.19 | 0.085 |
| Plasma cells (%) | 4.40 10.25 | 2.64 2.24 | 7.35 16.28 | 0.139 |
| Lymphoid cells (%) | 15.59 11.56 | 12.99 7.77 | 19.74 15.10 | 0.029* |
| Iron store (grade) | 2.41 1.33 | 2.35 1.16 | 2.54 1.66 | 0.713 |
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