Goal-Directed Resuscitation Aiming Cardiac Index Masks Residual Hypovolemia: An Animal Experiment

Figure 1

Flow chart. Schematic diagram illustrating the flowchart of the experimental protocol. After baseline measurement, animals were bled until the stroke volume index (SVI) decreased by 50% (); then measurements were repeated and randomized into two group. In the SVI-group the difference of the was divided into four equal target values (), and fluid resuscitated to reach the initial SVI by . In the CI-group the difference of the was divided into 4 target values and then the animals were resuscitated in 4 steps in order to reach the by .