Goal-Directed Resuscitation Aiming Cardiac Index Masks Residual Hypovolemia: An Animal Experiment
Table 3
Blood gas parameters during hemorrhage and fluid resuscitation.
Group
Oxygen delivery index (mL/min/m)
SVI
417 ± 64
250 ± 100
275 ± 71
291 ± 55
318 ± 55
337 ± 81
CI
410 ± 54
271 ± 62
297 ± 85
282 ± 47
278 ± 52
311 ± 61
Oxygen consumption (index mL/min/m)
SVI
82 ± 27
118 ± 63
111 ± 19
102 ± 24
98 ± 24
94 ± 23
CI
71 ± 43
115 ± 48
111 ± 29
108 ± 21
103 ± 18
99 ± 13
Oxygen extraction (VO/DO)
SVI
0.20 ± 0.06
0.40 ± 0.11
0.36 ± 0.06
0.33 ± 0.11
0.29 ± 0.09
0.27 ± 0.13
CI
0.17 ± 0.09
0.40 ± 0.18
0.38 ± 0.09
0.36 ± 0.08
0.34 ± 0.14
0.33 ± 0.11
Arterial pH
SVI
7.48 ± 0.04
7.46 ± 0.07
7.44 ± 0.06
7.41 ± 0.11
7.45 ± 0.04
7.46 ± 0.04
CI
7.44 ± 0.04
7.43 ± 0.06
7.42 ± 0.05
7.47 ± 0.03
7.42 ± 0.05
7.45 ± 0.05
Partial pressure of oxygen in arterial blood (mmHg)
SVI
94.5 ± 26.5
94.9 ± 27.8
90.1 ± 20.2
94.9 ± 27.1
93.1 ± 27.1
95.5 ± 30.1
CI
88.3 ± 28.8
89.8 ± 28.8
97.6 ± 30.2
89.2 ± 22.5
93.8 ± 32.6
88.2 ± 27.6
Arterial oxygen saturation (%)
SVI
97.3 ± 1.5
96.7 ± 2.1
96.3 ± 2.0
97.0 ± 1.5
97.0 ± 1.7
96.9 ± 1.8
CI
95.4 ± 3.6
95.3 ± 5.0
96.1 ± 4.2
98.6 ± 1.5
95.6 ± 4.8
96.0 ± 3.2
Central venous oxygen saturation (%)
SVI
77.4 ± 6.6
57.5 ± 10.8
60.9 ± 4.8
64.3 ± 9.2
68.4 ± 8.6
72.9 ± 7.5
CI
79.2 ± 8.1
56.7 ± 17.0
58.5 ± 10.6
59.7 ± 8.0
63.0 ± 14.7
64.1 ± 11.6
Venous to arterial carbon dioxide gap (mmHg)
SVI
5.7 ± 2.4
10.1 ± 2.6
8.9 ± 1.7
7.5 ± 2.4
7.2 ± 2.7
5.3 ± 2.3
CI
4.0 ± 3.1
9.9 ± 6.0
8.8 ± 2.4
8.5 ± 3.0
8.1 ± 3.1
7.6 ± 4.3
Lactate (mmol/L)
SVI
2.54 ± 1.01
3.97 ± 1.80
4.72 ± 2.29
4.37 ± 2.37
3.90 ± 2.25
3.26 ± 1.95
CI
3.32 ± 1.26
4.49 ± 1.83
4.50 ± 2.40
4.32 ± 0.69
4.05 ± 2.52
3.77 ± 2.32
Hemoglobin (g/dL)
SVI
11.6 ± 1.5
10.7 ± 1.5
10.4 ± 1.46
9.4 ± 1.2
8.3 ± 1.5
8.1 ± 0.9
CI
11.2 ± 0.7
10.4 ± 1.2
9.5 ± 1.2
9.2 ± 0.9
8.4 ± 0.6
8.2 ± 1.5
SVI (stroke volume index), SVI-group; CI (cardiac index), CI-group. Data are presented as mean ± standard deviation. significantly different from . significantly different from . significantly different between groups.
