HFE Genotyping in Patients with Elevated Serum Iron Indices and Liver Diseases
Table 1
Characteristics of patients.
Characteristic
HFE-HH ( = 16)
Non-HFE-HH iron elevation ( = 92)
Age, mean ± SD
51.07 ± 9.6
45.92 ± 13.65
Male, (%)
12 (75.0)
72 (78.26)
Caucasoid, (%)
11 (68.75)
65 (70.65)
Risk factors for elevated iron indices
Nonalcoholic liver disease, / (%)
3 /16 (18.75)
32/85 (37.65)
Alcoholic disease, / (%)
2/15 (13.3)
25/89 (28.09)
Chronic hepatitis C, / (%)
1/16 (6.25)
25/89 (28.09)
Porphyria cutanea tarda, / (%)
0/16 (0)
1/92 (7.69)
Human immune deficiency virus, / (%)
0/16 (0)
4/92 (4.35)
Chronic hepatitis B, / (%)
0/16 (0)
2/88 (2.27)
Chronic kidney disease, / (%)
0/16 (0)
2/90 (2.22)
HFE-HH: HFE hereditary hemochromatosis. Non-HFE-HH iron elevation: patients with iron elevation not related to HFE-HH genotypes. = number of patients affected. = total number of individuals assessed.