HFE Genotyping in Patients with Elevated Serum Iron Indices and Liver Diseases

Table 1

Characteristics of patients.

Characteristic	HFE-HH ( = 16)	Non-HFE-HH iron elevation ( = 92)
Age, mean ± SD	51.07 ± 9.6	45.92 ± 13.65
Male, (%)	12 (75.0)	72 (78.26)
Caucasoid, (%)	11 (68.75)	65 (70.65)
Risk factors for elevated iron indices
Nonalcoholic liver disease, / (%)	3 /16 (18.75)	32/85 (37.65)
Alcoholic disease, / (%)	2/15 (13.3)	25/89 (28.09)
Chronic hepatitis C, / (%)	1/16 (6.25)	25/89 (28.09)
Porphyria cutanea tarda, / (%)	0/16 (0)	1/92 (7.69)
Human immune deficiency virus, / (%)	0/16 (0)	4/92 (4.35)
Chronic hepatitis B, / (%)	0/16 (0)	2/88 (2.27)
Chronic kidney disease, / (%)	0/16 (0)	2/90 (2.22)

HFE-HH: HFE hereditary hemochromatosis.
Non-HFE-HH iron elevation: patients with iron elevation not related to HFE-HH genotypes.
= number of patients affected.
= total number of individuals assessed.