Proregenerative Microenvironment Triggered by Donor Mesenchymal Stem Cells Preserves Renal Function and Structure in Mice with Severe Diabetes Mellitus

Figure 1

MSC administration reduces glomerular hypertrophic alterations. Representative photomicrographs of kidney sections stained with PAS emphasizing in the glomeruli area, two and eight weeks after MSC administration (a). Quantitative analysis of renal corpuscle area (b) and glomerular tuft area (c) two and eight weeks after MSC administration. Data are presented as mean ± SEM, . versus Normal for the same time point. Bar = 25 μm.

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