Research Article

In Vitro Antiproliferative Effect of the Acetone Extract of Rubus fairholmianus Gard. Root on Human Colorectal Cancer Cells

Table 1

Trypan blue viability and LDH cytotoxicity assays.

GroupsViability percentageLDH cytotoxicity

Control83.83 ± 1.280.3490 ± 0.02
0.5% DMSO82.83 ± 0.980.3677 ± 0.02
5 g/mL RFRA71.33 ± 2.750.4580 ± 0.07
10 g/mL RFRA61.50 ± 2.540.5328 ± 0.06
20 g/mL RFRA52.50 ± 3.340.5943 ± 0.07
40 g/mL RFRA41.00 ± 3.590.6508 ± 0.06

Values are mean ± standard error of six independent assays performed in duplicates. The significant differences between treated and controls groups are shown as and . (RFRA: R. fairholmianus root acetone extract; LDH: lactate dehydrogenase; DMSO: dimethyl sulfoxide.)