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BioMed Research International
Volume 2015, Article ID 165908, 8 pages
Clinical Study

Patient-Specific CT-Based Instrumentation versus Conventional Instrumentation in Total Knee Arthroplasty: A Prospective Randomized Controlled Study on Clinical Outcomes and In-Hospital Data

1Department of Orthopedic Surgery and Traumatology, Central Research Hospital of Ministry of Interior, Wołoska 137, 02-507 Warsaw, Poland
2Department of Orthopaedics and Traumatology of Musculoskeletal System, 1st Faculty of Medicine, Medical University of Warsaw, ul. Lindleya 4, 02-005 Warsaw, Poland
3School of Medicine with the Division of Dentistry in Zabrze, Chair and Department of Descriptive and Topographic Anatomy, Medical University of Silesia, ul. Jordana 19, 41-808 Zabrze, Poland
4Department of Kinesiotherapy and Manual Therapy, Faculty of Health Sciences, Vincent Pol University in Lublin, ul. Choiny 2, 20-816 Lublin, Poland
5Head of Institute of Physiotherapy, The Jan Kochanowski University of Humanities and Sciences, al. IX Wieków 19, 25-317 Kielce, Poland
6Department of Physiotherapy, Faculty of Health and Medicine Science, Andrzej Frycz Modrzewski Cracow University, ul. Gustawa Herling Grudzińskiego 1, 30-705 Kraków, Poland
7Department of Physiotherapy, The Jan Kochanowski University of Humanities and Sciences, al. IX Wieków 19, 25-317 Kielce, Poland

Received 25 January 2015; Accepted 8 July 2015

Academic Editor: Giulio Gasparini

Copyright © 2015 Andrzej Kotela et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Total knee arthroplasty (TKA) is a frequently performed procedure in orthopaedic surgery. Recently, patient-specific instrumentation was introduced to facilitate correct positioning of implants. The aim of this study was to compare the early clinical results of TKA performed with patient-specific CT-based instrumentation and conventional technique. A prospective, randomized controlled trial on 112 patients was performed between January 2011 and December 2011. A group of 112 patients who met the inclusion and exclusion criteria were enrolled in this study and randomly assigned to an experimental or control group. The experimental group comprised 52 patients who received the Signature CT-based implant positioning system, and the control group consisted of 60 patients with conventional instrumentation. Clinical outcomes were evaluated with the KSS scale, WOMAC scale, and VAS scales to assess knee pain severity and patient satisfaction with the surgery. Specified in-hospital data were recorded. Patients were followed up for 12 months. At one year after surgery, there were no statistically significant differences between groups with respect to clinical outcomes and in-hospital data, including operative time, blood loss, hospital length of stay, intraoperative observations, and postoperative complications. Further high-quality investigations of various patient-specific systems and longer follow-up may be helpful in assessing their utility for TKA.