Research Article

A Population-Based Model to Consider the Effect of Seasonal Variation on Serum 25(OH)D and Vitamin D Status

Table 1

Participants’ characteristics for CoLaus and Bus Santé studies.

CoLaus studyBus Santé study () value1 value2 value3
Participants with vitamin D supplementation excluded ()Participants with vitamin D supplementation ()Participants with and without vitamin D supplementation ()

Age, mean (SD)49.77 (8.54)55.97 (7.30)49.96 (8.57)53.94 (6.73)<0.001<0.001<0.001
Male gender, (%)2421 (49.3)15 (9.7)2436 (48.1)1165 (45.9)<0.0010.0060.075
Height, cm, mean (SD)169.27 (9.26)164.59 (7.52)169.13 (9.24)168.66 (9.40)<0.0010.0080.041
Weight, kg, mean (SD)73.59 (14.19)64.73 (11.96)73.32 (14.21)72.30 (14.09)<0.001<0.0010.003
BMI, kg/m2, mean (SD)25.61 (4.12)23.85 (3.67)25.56 (4.12)25.32 (3.94)<0.0010.0030.015
25(OH)D, nmol/L, mean (SD)47.58 (22.10)66.05 (21.02)48.14 (22.29)48.62 (23.75)<0.0010.0610.389
25(OH)D < 50 nmol/L, (%)2827 (57.5)35 (22.7)2862 (56.5)1442 (56.8)<0.0010.5550.775
25(OH)D 50–75 nmol/L, (%)1528 (31.1)64 (41.6)1592 (31.4)776 (30.6)0.0060.6450.457

value comparing CoLaus study participants with and without vitamin D supplementation.
value comparing CoLaus study participants without vitamin D supplementation and Bus Santé.
value comparing CoLaus study (participants with and without vitamin D supplementation) and Bus Santé.
Based on corrected 25(OH)D values.