Comparative Analysis of Quinolone Resistance in Clinical Isolates of Klebsiella pneumoniae and Escherichia coli from Chinese Children and Adults

Table 1

Resistance of 140 K. pneumoniae and E. coli isolates to antimicrobial agents in children and adults.

Antimicrobial agent	K. pneumonia ( = 77)				E. coli ( = 63)
	Children	Adults	value	OR 95% CL	Children	Adults	value	OR 95% CL
	( = 38)	( = 39)			( = 23)	( = 40)
Ciprofloxacin	60.5 (23)	69.2 (27)	0.4235	(0.2659, 1.7464)	65.2 (15)	72.5 (29)	0.5443	(0.2359, 2.1443)
Levofloxacin	34.2 (13)	33.3 (13)	0.9351	(0.4044, 2.6748)	43.5 (10)	65.0 (26)	0.0965	(0.1450, 1.1832)
Cefoxitin	10.5 (4)	35.9 (14)	0.0085^*	(0.0617, 0.7154)	4.3 (1)	12.5 (5)	0.4022	(0.0348, 2.9070)
Cefotaxime	76.3 (29)	46.2 (18)	0.0067^*	(1.4143, 9.9920)	52.2 (12)	52.5 (21)	0.9801	(0.3535, 2.7560)
Ceftriaxone	71.1 (27)	48.7 (19)	0.0457^*	(1.0081, 6.6219)	56.5 (13)	52.5 (21)	0.7578	(0.4191, 3.3007
Cefoperazone	50.0 (19)	51.3 (20)	0.9104	(0.3887, 2.3218)	65.2 (15)	55.0 (22)	0.4277	(0.5131, 4.4294)
Ceftazidime	71.1 (27)	41.0 (16)	0.008^*	(1.3674, 9.1048)	13.0 (3)	25.0 (10)	0.3417	(0.1100, 1.8410)
Cefepime	21.1 (8)	15.4 (6)	0.5191	(0.4560, 4.7175)	26.1 (6)	25.0 (10)	0.9042	(0.3273, 3.4254)
Aztreonam	63.2 (24)	43.6 (17)	0.0853	(0.8896, 5.5324)	30.4 (7)	37.5 (15)	0.5712	(0.2440, 2.1792)
Gentamicin	57.9 (22)	43.6 (17)	0.2094	(0.7213, 4.3895)	60.9 (14)	77.5 (31)	0.1595	(0.1475, 1.3826)
Amikacin	76.3 (29)	38.5 (15)	0.0008^*	(1.9202, 13.8422)	4.3 (1)	17.5 (7)	0.2394	(0.0246, 1.8648)
Amoxycillin/Clavulanate	18.4 (7)	30.8 (12)	0.2089	(0.1751, 1.4744)	13.0 (3)	5.0 (2)	0.3453	(0.4395, 18.4792)
Piperacillin/Tazobactam	5.3 (2)	5.1 (2)	1.0000	(0.1373, 7.6933)	8.7 (2)	10.0 (4)	1.0000	(0.1445, 5.0861)

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