Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2015, Article ID 168294, 10 pages
http://dx.doi.org/10.1155/2015/168294
Research Article

Potential of Newborn and Adult Stem Cells for the Production of Vascular Constructs Using the Living Tissue Sheet Approach

1Université Laval Experimental Organogenesis Center/LOEX, Enfant-Jesus Hospital, 1401 18th rue, Québec, QC, Canada G1J 1Z4
2Regenerative Medicine Section, CHU de Québec Research Centre, Québec, QC, Canada G1J 1Z4
3Department of Surgery, Faculty of Medicine, Université Laval, Québec, QC, Canada G1V 0A6
4Maisonneuve-Rosemont Hospital Research Center, 415 Assomption boulevard, Montreal, QC, Canada H1T 2M4
5Department of Ophthalmology, University of Montreal, Montreal, QC, Canada H3T 1J4
6Quebec Center for Functional Materials (CQMF), Office 2634, Alexandre-Vachon Building, Université Laval, Québec, QC, Canada G1V 0A6
7Bordeaux Segalen University, INSERM-U1026, 146 Léo Saignat Street, 33000 Bordeaux, France

Received 19 February 2015; Revised 23 April 2015; Accepted 24 April 2015

Academic Editor: Magali Cucchiarini

Copyright © 2015 Jean-Michel Bourget et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. Mozaffarian, E. J. Benjamin, A. S. Go et al., “Executive summary: heart disease and stroke statistics-2015 update: a report from the american heart association,” Circulation, vol. 131, no. 4, pp. 434–441, 2015. View at Google Scholar
  2. K. A. Eagle, R. A. Guyton, R. Davidoff et al., “ACC/AHA 2004 guideline update for coronary artery bypass graft surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery),” Circulation, vol. 110, no. 14, pp. e340–e437, 2004. View at Google Scholar · View at Scopus
  3. R. E. Harskamp, R. D. Lopes, C. E. Baisden, R. J. De Winter, and J. H. Alexander, “Saphenous vein graft failure after coronary artery bypass surgery: pathophysiology, management, and future directions,” Annals of Surgery, vol. 257, no. 5, pp. 824–833, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Morishita, T. Shimakura, M. Miyagishima, J. Kawamoto, and H. Morimoto, “Minimally invasive direct redo coronary artery bypass grafting,” Annals of Thoracic and Cardiovascular Surgery, vol. 8, no. 4, pp. 209–212, 2002. View at Google Scholar · View at Scopus
  5. W. S. Weintraub, M. V. Grau-Sepulveda, J. M. Weiss et al., “Comparative effectiveness of revascularization strategies,” The New England Journal of Medicine, vol. 366, no. 16, pp. 1467–1476, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. L. E. Niklason, J. Gao, W. M. Abbott et al., “Functional arteries grown in vitro,” Science, vol. 284, no. 5413, pp. 489–493, 1999. View at Publisher · View at Google Scholar · View at Scopus
  7. B. V. Udelsman, M. W. Maxfield, and C. K. Breuer, “Tissue engineering of blood vessels in cardiovascular disease: moving towards clinical translation,” Heart, vol. 99, no. 7, pp. 454–460, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. F. A. Auger, M. Rémy-Zolghadri, G. Grenier, and L. Germain, “Review: the self-assembly approach for organ reconstruction by tissue engineering,” e-biomed: The Journal of Regenerative Medicine, vol. 1, no. 5, pp. 75–86, 2000. View at Publisher · View at Google Scholar
  9. N. L'Heureux, S. Pâquet, R. Labbé, L. Germain, and F. A. Auger, “A completely biological tissue-engineered human blood vessel,” The FASEB Journal, vol. 12, no. 1, pp. 47–56, 1998. View at Google Scholar · View at Scopus
  10. G. Grenier, M. Rémy-Zolghadri, R. Guignard et al., “Isolation and culture of the three vascular cell types from a small vein biopsy sample,” In Vitro Cellular & Developmental Biology—Animal, vol. 39, no. 3-4, pp. 131–139, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. R. Gauvin, M. Guillemette, T. Galbraith et al., “Mechanical properties of tissue-engineered vascular constructs produced using arterial or venous cells,” Tissue Engineering Part A, vol. 17, no. 15-16, pp. 2049–2059, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. N. G. Singer and A. I. Caplan, “Mesenchymal stem cells: mechanisms of inflammation,” Annual Review of Pathology, vol. 6, pp. 457–478, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. M. C. Galmiche, V. E. Koteliansky, J. Briere, P. Herve, and P. Charbord, “Stromal cells from human long-term marrow cultures are mesenchymal cells that differentiate following a vascular smooth muscle differentiation pathway,” Blood, vol. 82, no. 1, pp. 66–76, 1993. View at Google Scholar · View at Scopus
  14. A. I. Caplan, “Mesenchymal stem cells,” Journal of Orthopaedic Research, vol. 9, no. 5, pp. 641–650, 1991. View at Publisher · View at Google Scholar · View at Scopus
  15. A. I. Caplan, “Review: mesenchymal stem cells: cell-based reconstructive therapy in orthopedics,” Tissue Engineering, vol. 11, no. 7-8, pp. 1198–1211, 2005. View at Publisher · View at Google Scholar · View at Scopus
  16. A. I. Caplan, “Adult mesenchymal stem cells for tissue engineering versus regenerative medicine,” Journal of Cellular Physiology, vol. 213, no. 2, pp. 341–347, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. L. D. S. Meirelles, A. I. Caplan, and N. B. Nardi, “In search of the in vivo identity of mesenchymal stem cells,” Stem Cells, vol. 26, no. 9, pp. 2287–2299, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. A. I. Caplan, “All MSCs are pericytes?” Cell Stem Cell, vol. 3, no. 3, pp. 229–230, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Crisan, S. Yap, L. Casteilla et al., “A perivascular origin for mesenchymal stem cells in multiple human organs,” Cell Stem Cell, vol. 3, no. 3, pp. 301–313, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. C. J. Hayward, J. Fradette, T. Galbraith et al., “Harvesting the potential of the human umbilical cord: isolation and characterisation of four cell types for tissue engineering applications,” Cells Tissues Organs, vol. 197, no. 1, pp. 37–54, 2012. View at Publisher · View at Google Scholar · View at Scopus
  21. C. J. Hayward, J. Fradette, P. Morissette Martin, R. Guignard, L. Germain, and F. A. Auger, “Using human umbilical cord cells for tissue engineering: a comparison with skin cells,” Differentiation, vol. 87, no. 3-4, pp. 172–181, 2014. View at Publisher · View at Google Scholar
  22. M. Vermette, V. Trottier, V. Ménard, L. Saint-Pierre, A. Roy, and J. Fradette, “Production of a new tissue-engineered adipose substitute from human adipose-derived stromal cells,” Biomaterials, vol. 28, no. 18, pp. 2850–2860, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. A. Rousseau, J. Fradette, G. Bernard, R. Gauvin, V. Laterreur, and S. Bolduc, “Adipose-derived stromal cells for the reconstruction of a human vesical equivalent,” Journal of Tissue Engineering and Regenerative Medicine, 2013. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Kaushal, G. E. Amiel, K. J. Guleserian et al., “Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo,” Nature Medicine, vol. 7, no. 9, pp. 1035–1040, 2001. View at Publisher · View at Google Scholar · View at Scopus
  25. M. F. Pittenger, A. M. Mackay, S. C. Beck et al., “Multilineage potential of adult human mesenchymal stem cells,” Science, vol. 284, no. 5411, pp. 143–147, 1999. View at Publisher · View at Google Scholar · View at Scopus
  26. D. Larouche, C. Paquet, J. Fradette, P. Carrier, F. A. Auger, and L. Germain, “Regeneration of skin and cornea by tissue engineering,” Methods in Molecular Biology, vol. 482, pp. 233–256, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. R. Ross, “The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers,” The Journal of Cell Biology, vol. 50, no. 1, pp. 172–186, 1971. View at Publisher · View at Google Scholar · View at Scopus
  28. J.-M. Bourget, R. Gauvin, D. Larouche et al., “Human fibroblast-derived ECM as a scaffold for vascular tissue engineering,” Biomaterials, vol. 33, no. 36, pp. 9205–9213, 2012. View at Publisher · View at Google Scholar · View at Scopus
  29. K. Laflamme, C. J. Roberge, S. Pouliot, P. D'Orléans-Juste, F. A. Auger, and L. Germain, “Tissue-engineered human vascular media produced in vitro by the self-assembly approach present functional properties similar to those of their native blood vessels,” Tissue Engineering, vol. 12, no. 8, pp. 2275–2281, 2006. View at Publisher · View at Google Scholar · View at Scopus
  30. L. G. Luna, Manual of Histologic Staining Methods of the Armed Forces Institute of Pathology, Blakiston Division, McGraw-Hill, New York, NY, USA, 1968.
  31. P. Masson, “Some histological methods: trichrome staining and their preliminary technique,” Journal of Technical Methods—Bulletin of the International Association of Medical Museums, vol. 12, no. 75, 1929. View at Google Scholar
  32. R. Gauvin, T. Ahsan, D. Larouche et al., “A novel single-step self-assembly approach for the fabrication of tissue-engineered vascular constructs,” Tissue Engineering Part A, vol. 16, no. 5, pp. 1737–1747, 2010. View at Publisher · View at Google Scholar · View at Scopus
  33. D. Seliktar, R. A. Black, R. P. Vito, and R. M. Nerem, “Dynamic mechanical conditioning of collagen-gel blood vessel constructs induces remodeling in vitro,” Annals of Biomedical Engineering, vol. 28, no. 4, pp. 351–362, 2000. View at Publisher · View at Google Scholar · View at Scopus
  34. N. L'Heureux, J.-C. Stoclet, F. A. Auger, G. J.-L. Lagaud, L. Germain, and R. Andriantsitohaina, “A human tissue-engineered vascular media: a new model for pharmacological studies of contractile responses,” The FASEB Journal, vol. 15, no. 2, pp. 515–524, 2001. View at Publisher · View at Google Scholar · View at Scopus
  35. M. Pricci, J.-M. Bourget, H. Robitaille et al., “Applications of human tissue-engineered blood vessel models to study the effects of shed membrane microparticles from T-lymphocytes on vascular function,” Tissue Engineering Part A, vol. 15, no. 1, pp. 137–145, 2009. View at Publisher · View at Google Scholar · View at Scopus
  36. M. R. Alexander and G. K. Owens, “Epigenetic control of smooth muscle cell differentiation and phenotypic switching in vascular development and disease,” Annual Review of Physiology, vol. 74, pp. 13–40, 2012. View at Publisher · View at Google Scholar · View at Scopus
  37. B. L. Bader, L. Jahn, and W. W. Franke, “Low level expression of cytokeratins 8, 18 and 19 in vascular smooth muscle cells of human umbilical cord and in cultured cells derived therefrom, with an analysis of the chromosomal locus containing the cytokeratin 19 gene,” European Journal of Cell Biology, vol. 47, no. 2, pp. 300–319, 1988. View at Google Scholar · View at Scopus
  38. H. Bär, F. Bea, E. Blessing et al., “Phosphorylation of cytokeratin 8 and 18 in human vascular smooth muscle cells of atherosclerotic lesions and umbilical cord vessels,” Basic Research in Cardiology, vol. 96, no. 1, pp. 50–58, 2001. View at Publisher · View at Google Scholar · View at Scopus
  39. L. Jahn, J. Kreuzer, E. von Hodenberg et al., “Cytokeratins 8 and 18 in smooth muscle cells: detection in human coronary artery, peripheral vascular, and vein graft disease and in transplantation-associated arteriosclerosis,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 13, no. 11, pp. 1631–1639, 1993. View at Publisher · View at Google Scholar · View at Scopus
  40. C. Su and J. A. Bevan, “The electrical response of pulmonary artery muscle to acetylcholine, histamine and serotonin,” Life Sciences, vol. 4, no. 10, pp. 1025–1029, 1965. View at Publisher · View at Google Scholar · View at Scopus
  41. P. M. Hudgins and G. B. Weiss, “Differential effects of calcium removal upon vascular smooth muscle contraction induced by norepinephrine, histamine and potassium,” The Journal of Pharmacology and Experimental Therapeutics, vol. 159, no. 1, pp. 91–97, 1968. View at Google Scholar · View at Scopus
  42. H. A. Mostefai, J.-M. Bourget, F. Meziani et al., “Interleukin-10 controls the protective effects of circulating microparticles from patients with septic shock on tissue-engineered vascular media,” Clinical Science, vol. 125, no. 2, pp. 77–85, 2013. View at Publisher · View at Google Scholar · View at Scopus
  43. S. J. Hill, C. R. Ganellin, H. Timmerman et al., “International union of pharmacology. XIII. Classification of histamine receptors,” Pharmacological Reviews, vol. 49, no. 3, pp. 253–278, 1997. View at Google Scholar · View at Scopus
  44. J. J. Bara, R. G. Richards, M. Alini, and M. J. Stoddart, “Concise review: bone marrow-derived mesenchymal stem cells change phenotype following in vitro culture: implications for basic research and the clinic,” Stem Cells, vol. 32, no. 7, pp. 1713–1723, 2014. View at Publisher · View at Google Scholar
  45. F. Bortolotti, L. Ukovich, V. Razban et al., “In vivo therapeutic potential of mesenchymal stromal cells depends on the source and the isolation procedure,” Stem Cell Reports, vol. 4, no. 3, pp. 332–339, 2015. View at Publisher · View at Google Scholar
  46. D. L. Coutu, W. Mahfouz, O. Loutochin, J. Galipeau, and J. Corcos, “Tissue engineering of rat bladder using marrow-derived mesenchymal stem cells and bladder acellular matrix,” PLoS ONE, vol. 9, no. 12, Article ID e111966, 2014. View at Publisher · View at Google Scholar
  47. D. Kai, M. P. Prabhakaran, G. Jin, L. Tian, and S. Ramakrishna, “Potential of VEGF-encapsulated electrospun nanofibers for in vitro cardiomyogenic differentiation of human mesenchymal stem cells,” Journal of Tissue Engineering and Regenerative Medicine, 2015. View at Publisher · View at Google Scholar
  48. V. Savkovic, H. Li, J. K. Seon, M. Hacker, S. Franz, and J. C. Simon, “Mesenchymal stem cells in cartilage regeneration,” Current Stem Cell Research & Therapy, vol. 9, no. 6, pp. 469–488, 2014. View at Publisher · View at Google Scholar
  49. J. F. Stoltz, D. Bensoussan, L. Zhang et al., “Stem cells and applications: a survey,” Bio-Medical Materials and Engineering, vol. 25, no. 1, supplement, pp. 3–26, 2015. View at Publisher · View at Google Scholar
  50. H. Huang and S. Hsu, “Current advances of stem cell-based approaches to tissue-engineered vascular grafts,” OA Tissue Engineering, vol. 1, no. 1, 2013. View at Publisher · View at Google Scholar
  51. E. D. O'Cearbhaill, M. Murphy, F. Barry, P. E. McHugh, and V. Barron, “Behavior of human mesenchymal stem cells in fibrin-based vascular tissue engineering constructs,” Annals of Biomedical Engineering, vol. 38, no. 3, pp. 649–657, 2010. View at Publisher · View at Google Scholar · View at Scopus
  52. L. Dainese, A. Guarino, I. Burba et al., “Heart valve engineering: decellularized aortic homograft seeded with human cardiac stromal cells,” The Journal of Heart Valve Disease, vol. 21, no. 1, pp. 125–134, 2012. View at Google Scholar · View at Scopus
  53. C. Quint, Y. Kondo, R. J. Manson, J. H. Lawson, A. Dardik, and L. E. Niklason, “Decellularized tissue-engineered blood vessel as an arterial conduit,” Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 22, pp. 9214–9219, 2011. View at Publisher · View at Google Scholar · View at Scopus
  54. L. Soletti, Y. Hong, J. Guan et al., “A bilayered elastomeric scaffold for tissue engineering of small diameter vascular grafts,” Acta Biomaterialia, vol. 6, no. 1, pp. 110–122, 2010. View at Publisher · View at Google Scholar · View at Scopus
  55. A. Nieponice, L. Soletti, J. Guan et al., “In Vivo assessment of a tissue-engineered vascular graft combining a biodegradable elastomeric scaffold and muscle-derived stem cells in a rat model,” Tissue Engineering—Part A, vol. 16, no. 4, pp. 1215–1223, 2010. View at Publisher · View at Google Scholar · View at Scopus
  56. H. L. Sang, S.-W. Cho, J.-C. Park et al., “Tissue-engineered blood vessels with endothelial nitric oxide synthase activity,” Journal of Biomedical Materials Research Part B: Applied Biomaterials, vol. 85, no. 2, pp. 537–546, 2008. View at Publisher · View at Google Scholar · View at Scopus
  57. L. Jia, M. P. Prabhakaran, X. Qin, and S. Ramakrishna, “Stem cell differentiation on electrospun nanofibrous substrates for vascular tissue engineering,” Materials Science & Engineering C, vol. 33, no. 8, pp. 4640–4650, 2013. View at Publisher · View at Google Scholar · View at Scopus
  58. M. P. Prabhakaran, L. Ghasemi-Mobarakeh, and S. Ramakrishna, “Electrospun composite nanofibers for tissue regeneration,” Journal of Nanoscience and Nanotechnology, vol. 11, no. 4, pp. 3039–3057, 2011. View at Publisher · View at Google Scholar · View at Scopus
  59. F. Wang, Z. Li, and J. Guan, “Fabrication of mesenchymal stem cells-integrated vascular constructs mimicking multiple properties of the native blood vessels,” Journal of Biomaterials Science Polymer Edition, vol. 24, no. 7, pp. 769–783, 2013. View at Publisher · View at Google Scholar · View at Scopus
  60. J. Zhao, L. Liu, J. Wei et al., “A novel strategy to engineer small-diameter vascular grafts from marrow-derived mesenchymal stem cells,” Artificial Organs, vol. 36, no. 1, pp. 93–101, 2012. View at Publisher · View at Google Scholar · View at Scopus
  61. L. Ren, D. Ma, B. Liu et al., “Preparation of three-dimensional vascularized MSC cell sheet constructs for tissue regeneration,” BioMed Research International, vol. 2014, Article ID 301279, 10 pages, 2014. View at Publisher · View at Google Scholar
  62. M. D. Guillemette, R. Gauvin, C. Perron, R. Labbé, L. Germain, and F. A. Auger, “Tissue-engineered vascular adventitia with vasa vasorum improves graft integration and vascularization through inosculation,” Tissue Engineering Part A, vol. 16, no. 8, pp. 2617–2626, 2010. View at Publisher · View at Google Scholar · View at Scopus
  63. P.-L. Tremblay, V. Hudon, F. Berthod, L. Germain, and F. A. Auger, “Inosculation of tissue-engineered capillaries with the host's vasculature in a reconstructed skin transplanted on mice,” American Journal of Transplantation, vol. 5, no. 5, pp. 1002–1010, 2005. View at Publisher · View at Google Scholar · View at Scopus
  64. G. Grenier, M. Rémy-Zolghadri, D. Larouche et al., “Tissue reorganization in response to mechanical load increases functionality,” Tissue Engineering, vol. 11, no. 1-2, pp. 90–100, 2005. View at Publisher · View at Google Scholar · View at Scopus
  65. R. Gauvin, R. Parenteau-Bareil, D. Larouche et al., “Dynamic mechanical stimulations induce anisotropy and improve the tensile properties of engineered tissues produced without exogenous scaffolding,” Acta Biomaterialia, vol. 7, no. 9, pp. 3294–3301, 2011. View at Publisher · View at Google Scholar · View at Scopus
  66. Z. Gong and L. E. Niklason, “Small-diameter human vessel wall engineered from bone marrow-derived mesenchymal stem cells (hMSCs),” The FASEB Journal, vol. 22, no. 6, pp. 1635–1648, 2008. View at Publisher · View at Google Scholar · View at Scopus
  67. T. M. Maul, D. W. Chew, A. Nieponice, and D. A. Vorp, “Mechanical stimuli differentially control stem cell behavior: morphology, proliferation, and differentiation,” Biomechanics and Modeling in Mechanobiology, vol. 10, no. 6, pp. 939–953, 2011. View at Publisher · View at Google Scholar · View at Scopus