Review Article

Development of Monoclonal Antibodies in China: Overview and Prospects

Table 2

mAb patents of China in USPTO.

Number  TitleIPCAssigneePublication date
(MM/DD/YYYY)

1Use of DKK-1 protein in the cancer diagnosisA61B 5/00 (20060101);
A61B 8/00 (20060101);
A61B 10/00 (20060101)
Shanghai Cancer Institute
(Shenzhen, CN)
12/27/2012

2Monoclonal antibodies binding to avian influenza virus subtype H5 hemagglutinin and uses thereofA61K 39/42 (20060101)Xiamen University
(Fujian Province, CN)
12/22/2011

3Fully human anti-TNF-alpha monoclonal antibody, preparation method, and use thereofA61K 39/395 (20060101);
C07K 16/24 (20060101);
C12N 5/10 (20060101);
C12N 15/13 (20060101);
C12N 15/00 (20060101)
Shanghai Biomabs Pharmaceuticals Co., Ltd. (Shanghai, CN)12/06/2012

4Anti-EFGRv3 monoclonal antibodyA61K 39/395 (20060101);
C12P 19/34 (20060101)
Shanghai Cancer Institute
(Shanghai, CN)
02/14/2013

5Use of DKK-1 protein in the cancer diagnosisA61K 51/00 (20060101);
A61M 36/14 (20060101)
Shanghai Cancer Institute
(Shanghai, CN)
05/14/2009

6Anti-VEGFR monoclonal antibody, method of making, and uses thereofA61K 39/395 (20060101);
C07K 16/00 (20060101);
A61K 39/00 (20060101);
C07K 16/28 (20060101)
Shanghai Aosaiersi Biotech Co., Ltd.
(Shanghai, CN)
02/17/2011

7Anti-human trail receptor DR5 monoclonal antibody (AD5-10), method thereof, and use of the sameC12P 21/08 (20060101);
C12N 5/16 (20100101);
C12N 5/07 (20100101); A61K39/395 (20060101);
C07K 16/00 (20060101)
The Institute of Basic Medical Sciences of Chinese Academy of Medical Sciences
(Beijing, CN)
04/01/2010

8Monoclonal antibody against hepatitis E virus or its fragment with binding activity and use thereofC12P 21/08 (20060101);
C07K 16/00 (20060101)
Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. (Haikou, CN) 10/19/2006

9Method and composition for diagnosis of melanocytic lesionsG01N 33/53 (20060101); G01N 33/574 (20060101)Shanghai CP GuoJian Pharmaceutical Co., Ltd.
(Shanghai, CN)
N/A

Notes: “IPC” is International Patent Classification. “Assignee” shows the contents of mAb patents belonging to Chinese applicants in United States Patent and Trade mark Office (USPTO).
Source: http://www.uspto.gov/.