Research Article

Lespedeza davurica (Lax.) Schindl. Extract Protects against Cytokine-Induced β-Cell Damage and Streptozotocin-Induced Diabetes

Table 2

Effect of LD extract on serum TC, TG, TBARS, and liver TBARS and glycogen levels in STZ-induced diabetic rats.

GroupSerum TCSerum TGSerum TBARSLiver TBARSLiver glycogen
(mg/dL)(mg/dL)(nM/mL)(nM/mg protein)(g/mg tissue)

Normal73 ± 5.3a80.0 ± 4.0a9.01 ± 0.2a1.32 ± 0.08a4.46 ± 0.37b
Control140 ± 10.0c256.4 ± 17.5c12.14 ± 0.3b2.92 ± 0.06d2.77 ± 0.10a
LD90 ± 4.5ab197.9 ± 24.4b8.96 ± 0.3a2.02 ± 0.07ab3.92 ± 0.45ab
TLB90 ± 5.3ab159.9 ± 28.6b11.75 ± 0.6b1.90 ± 0.05b3.86 ± 0.13ab

Values are means ± SE for each group of eight animals. Values with different letters are significantly different ( < 0.05, Duncan’s multiple comparison tests). LD (L. davurica) and TLB (tolbutamide) were administered at a dose of 250 mg/kg body weight for 4 weeks.