Adventitial Alterations Are the Main Features in Pulmonary Artery Remodeling due to Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats

Figure 3

Media layer: (a) cross-sectional area (CSAm) of media layer in square microns (μm²), (b) total number of smooth muscle cells (SMCs μm/1 mm length artery), (c) total cell density (SMCs/layer volume mm³), and (d) representative confocal reconstructions obtained of the PA SMCs from 15 serial medial layer images of pulmonary arteries from rats exposed to CIH2x2, CH, and NX (63x objective zoom 2). Values are expressed as the means ± SEs. Statistical analysis was performed using one-way ANOVA.   is exposed versus NX and ^† CH versus CIH2x2.

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