Adventitial Alterations Are the Main Features in Pulmonary Artery Remodeling due to Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats

Figure 4

Adventitial layer: (a) adventitial CSA (μm²). (b) Adventitial total cell number/1 mm of artery (N°. cells/mm) measured under a 10x objective. (c) Total density (cell number/layer volume; mm³) and (d) representative confocal reconstructions obtained from the adventitial layer of PAs (63x objective zoom) from rats exposed to CIH2x2, CH, and NX. Results are expressed as means ± SEs; statistical analysis was performed using one-way ANOVA.   is exposed versus NX and ^† for CH versus CIH2x2.

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