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BioMed Research International
Volume 2015 (2015), Article ID 170278, 6 pages
http://dx.doi.org/10.1155/2015/170278
Research Article

Toxoplasma gondii Infection in Pregnant Women: A Seroprevalence and Case-Control Study in Eastern China

1College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China
2State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu 730046, China
3Wendeng Stomatology Hospital, Weihai, Shandong 264200, China
4Jilin Entry-Exit Inspection and Quarantine Bureau, Changchun, Jilin 130118, China
5Affiliated Hospital of Medical College, Qingdao University, Qingdao, Shandong 266071, China
6Wendeng Municipal Hospital, Weihai, Shandong 264400, China

Received 24 May 2015; Revised 5 August 2015; Accepted 9 August 2015

Academic Editor: Sten H. Vermund

Copyright © 2015 Wei Cong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Very limited information is available concerning the epidemiology of T. gondii infection in pregnant women in eastern China. Therefore, a case-control study was conducted to estimate the seroprevalence of toxoplasmosis in this population group and to identify risk factors and possible routes of contamination. Serum samples were collected from 965 pregnant women and 965 age-matched nonpregnant control subjects in Qingdao and Weihai between October 2011 and July 2013. These were screened with enzyme linked immunoassays for the presence of anti-Toxoplasma IgG and anti-Toxoplasma IgM antibodies. 147 (15.2%) pregnant women and 167 (17.3%) control subjects were positive for anti-T. gondii IgG antibodies, while 28 (2.9%) pregnant women and 37 (3.8%) controls were positive for anti-T. gondii IgM antibodies (). There was no significant difference between pregnant women and nonpregnant controls with regard to the seroprevalence of either anti-T. gondii IgG or IgM antibodies. Multivariate analysis showed that T. gondii infection was associated with location, cats in home, contact with cats and dogs, and exposure to soil. The results indicated that the seroprevalence of T. gondii infection in pregnant women is high compared to most other regions of China and other East Asian countries with similar climatic conditions.