Research Article

Development of a Model of Chronic Kidney Disease in the C57BL/6 Mouse with Properties of Progressive Human CKD

Figure 3

Renal tissue damage in response to Ang II/DOCA salt CKD mouse model. For all graphs, indicates a significant difference between two groups where . Effect of Ang II/DOCA salt model on (a), (b) protein cast formation in the cortex and medulla, (c), (d) glomerulosclerosis, (e), (f) apoptosis, (g), (h) macrophage (F4/80+ cells) infiltration, and (i) interstitial fibrosis (Masson’s trichrome staining).