Research Article

Development of a Model of Chronic Kidney Disease in the C57BL/6 Mouse with Properties of Progressive Human CKD

Figure 5

Impact of gender on CKD induced by Ang II/DOCA salt model. For all graphs, indicates a significant difference between two groups where . Ang II/DOCA salt is denoted by ■, whereas □ denotes SHAM operated controls. “M” and “F” indicate sections from male and female mouse kidneys, respectively. Influence of gender on the development of (a) proteinuria, (b) albuminuria, (c) protein cast formation, (d) apoptosis, and (e) interstitial fibrosis.