Review Article

Mechanism of Action of Bortezomib and the New Proteasome Inhibitors on Myeloma Cells and the Bone Microenvironment: Impact on Myeloma-Induced Alterations of Bone Remodeling

Figure 1

Bortezomib and the new PIs. Chemical structure of bortezomib and the new PIs. PIs: proteasome inhibitors.