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BioMed Research International
Volume 2015, Article ID 174050, 9 pages
http://dx.doi.org/10.1155/2015/174050
Review Article

Glu504Lys Single Nucleotide Polymorphism of Aldehyde Dehydrogenase 2 Gene and the Risk of Human Diseases

1Department of Bioengineering, Harbin Institute of Technology at Weihai, Shandong 264209, China
2Department of Mathematics, Harbin Institute of Technology at Weihai, Shandong 264209, China

Received 7 May 2015; Revised 29 July 2015; Accepted 19 August 2015

Academic Editor: Jing Zhang

Copyright © 2015 Yan Zhao and Chuancai Wang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [9 citations]

The following is the list of published articles that have cited the current article.

  • Dong Jin Lee, Hyung Min Lee, Jin Hwan Kim, II Seok Park, and Young Soo Rho, “Heavy alcohol drinking downregulates ALDH2 gene expression but heavy smoking up-regulates SOD2 gene expression in head and neck squamous cell carcinoma,” World Journal of Surgical Oncology, vol. 15, no. 1, 2017. View at Publisher · View at Google Scholar
  • Min-Jeong Shin, Yoonsu Cho, and George Davey Smith, “Alcohol consumption, Aldehyde dehydrogenase 2 gene polymorphisms, and cardiovascular health in Korea,” Yonsei Medical Journal, vol. 58, no. 4, pp. 689–696, 2017. View at Publisher · View at Google Scholar
  • Tao Xu, Shuangyue Liu, Tingting Ma, Ziyi Jia, Zhifei Zhang, and Aimei Wang, “Aldehyde dehydrogenase 2 protects against oxidative stress associated with pulmonary arterial hypertension,” Redox Biology, vol. 11, pp. 286–296, 2017. View at Publisher · View at Google Scholar
  • Shuang Shao, Jing Sun, Hong-Jing Dong, Yan-Qing Li, Chun-Yan Liu, and Yan-Hang Gao, “Aldehyde dehydrogenase 2 gene polymorphisms and liver diseases,” World Chinese Journal of Digestology, vol. 25, no. 33, pp. 2981–2986, 2017. View at Publisher · View at Google Scholar
  • Minhao Hu, and Neil B. Piller, “Strategies for Avoiding Benzopyrone Hepatotoxicity in Lymphedema Management—The Role of Pharmacogenetics, Metabolic Enzyme Gene Identification, and Patient Selection,” Lymphatic Research and Biology, 2017. View at Publisher · View at Google Scholar
  • Ying Yu, Qin Gao, Wanning Xia, Lina Zhang, Zhiyuan Hu, Xuesen Wu, and Xianjie Jia, “Association between Physical Exercise and Biomarkers of Oxidative Stress among Middle-Aged and Elderly Community Residents with Essential Hypertension in China,” BioMed Research International, vol. 2018, pp. 1–11, 2018. View at Publisher · View at Google Scholar
  • Romina Deza-Ponzio, Macarena Lorena Herrera, María José Bellini, Miriam Beatriz Virgolini, and Claudia Beatriz Hereñú, “Aldehyde Dehydrogenase 2 in the spotlight: the link between mitochondria and neurodegeneration,” NeuroToxicology, 2018. View at Publisher · View at Google Scholar
  • Takuya Imatoh, Loic Yengo, Ghislain Rocheleau, Seiichiro Kamimura, Shiro Maeda, Motonobu Miyazaki, and Philippe Froguel, “ ALDH2 Polymorphism rs671, but Not ADH1B Polymorphism rs1229984, Increases Risk for Hypo-HDL-Cholesterolemia in a/a Carriers Compared to the G/G Carriers ,” Lipids, 2018. View at Publisher · View at Google Scholar
  • Miriam B. Virgolini, Mara S. Mattalloni, Romina Deza-Ponzio, Paula A. Albrecht, and Liliana M. Cancela, “Lead Exposure and Ethanol Intake: Oxidative Stress as a Converging Mechanism of Action,” Neuroscience of Alcohol, pp. 515–525, 2019. View at Publisher · View at Google Scholar