Ox-LDL Induces Dysfunction of Endothelial Progenitor Cells via Activation of NF-B

Figure 2

Effects of ox-LDL on EPC function. (a) Ox-LDL treatment inhibited proliferation of EPCs. EPCs were incubated in the presence or absence of ox-LDL for 24 hours as indicated. Cell proliferation was assayed by CCK8 method. (b) Ox-LDL decreased the number of adherent EPCs. EPCs were incubated in the presence or absence of ox-LDL as indicated, and adherent cells were counted. (c) Ox-LDL treatment inhibited migration of EPCs. Migration of EPCs exposed to ox-LDL was examined by transwell chemotaxis assay. Data are expressed as the means ± SEMs of triplicate experiments. versus control.

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