Activity of α₁-Antitrypsin and Some Lysosomal Enzymes in the Blood Serum of Patients with Chronic Obstructive Pulmonary Disease after Smoking Cessation

Table 1

Patient characteristics.

	Nonsmokers; —control I	COPD patients; —control II	COPD patients; —study group
Number of subjects	33	33	70
Age (years)	44.8 ± 15.2	47.7 ± 13.6	48.8 ± 12.1
Sex (F/M)	15/18	14/19	32/38
Smoking period (years)	—	31.4 ± 10.2	30.9 ± 13.5
Number of packs/year	—	292.0 ± 65.6	287.4 ± 78.3
FEV1 (% predicted value)	97.9 ± 13.9	72.9 ± 19.3	73.1 ± 17.5
FVC (% predicted value)	109.5 ± 13.5	94.1 ± 15.8	94.3 ± 18.2
FEV1/FVC (%)	84.9 ± 5.8	62.0 ± 7.1	61.5 ± 7.4

FEV₁: forced expiratory volume in 1 second; FVC: forced vital capacity; FEV₁/FVC: forced expiratory volume in 1 second/forced vital capacity ratio.
Data expressed as mean   ± SD.