BioMed Research International / 2015 / Article / Tab 3

Research Article

Early Fluid Resuscitation and High Volume Hemofiltration Decrease Septic Shock Progression in Swine

Table 3

Levels of serum inflammatory mediators.

Variable/groupBaselineUpon successful resuscitation1 h2 h3 h4 h5 h6 h

IL-6 (pg/mL)
 Control96 (75; 125)475 (449; 549)604 (533; 633)627 (602; 668)699 (663; 721)734 (718; 750)826 (785; 841)785 (775; 848)
 CRRT99 (87; 152)525 (475; 575)403.5 (387; 434)400 (387; 424)479 (460; 517)465 (425; 495)501 (454; 540)493 (482; 536)
 HVHF129 (92; 155)507 (472; 559)408.5 (390; 438)422 (404; 424)447.5 (411; 506)403 (394; 411)394 (344; 421)364 (294; 380)
0.3300.5810.0030.0030.0040.0010.0010.001
IL-10 (pg/mL)
 Control14 (11; 14)68 (60; 78)76 (72; 82)91 (86; 97)97 (91; 104)98 (97; 106)112 (101; 119)106 (100; 127)
 CRRT16 (8; 18)61 (56; 75)67 (64; 74)51 (49; 52)50 (48; 55)45 (42; 46)41 (34; 46)37 (31; 39)
 HVHF15 (12; 17)75 (66; 80)51 (46; 56)41 (38; 48)40 (34; 44)31 (28; 33)31 (27; 34)27 (25; 30)
0.4310.2770.0030.0010.0010.0010.0020.001

CRRT: continuous renal replacement therapy; HVHF: high volume hemofiltration.
between the CRRT and control groups, between the HVHF and control groups, between the CRRT and HVHF groups.

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