Recent Advances in Genetic Technique of Microbial Report Cells and Their Applications in Cell Arrays

Table 2

Representative advantages and challenges of microbial cell arrays.

Advantages	Challenges
(1) Analysis of global activities of target analyte	(1) Limited viability and biological function
(2) Low cost	(2) Insufficient specificity
(3) Analysis is more convenient than existing technologies	(3) Types of target analytes are limited
(4) Robust to reaction environments	(4) Genetic stability of engineered reporter cell system is low
(5) Simultaneous detection of multiple analytes	(5) Laws limiting the use of genetically modified organisms
(6) Real-time, in situ monitoring	(6) Slow diffusion in cell membranes