Evaluation of APP695 Transgenic Mice Bone Marrow Mesenchymal Stem Cells Neural Differentiation for Transplantation
APP695 MSCs had higher neuronal differentiation efficiency. The expression of NSE and MAP-2, 6 days after induction with β-ME. (a) The expression of MAP-2 and NSE by immunocytochemical staining is shown (scale bar: 20 μm). (b) The expression levels of NSE and MAP-2 in MSCs 6 days after induction with β-ME as analyzed by western blot. (c) The quantification of the expression levels of NSE and MAP-2 (mean ± SD; ). APP695 versus WT, * for NSE, and # for MAP-2.