Biomarker Identification and Pathway Analysis by Serum Metabolomics of Lung Cancer

Table 2

GC/MS identification of potential serum biomarkers in lung cancer.

Number	Retention time (min)	m/z	Metabolites	Relative mass intensity
				Control group	Preoperative lung cancer group (PRLC)	Postoperative lung cancer group (POLC)
1	9.21	131.1089	-Hydroxyisobutyric acid	306.84 ± 153.64	556.54 ± 220.00^*	803.58 ± 329.41^*
2	12.23	132.1187	Serine	183.48 ± 96.63	114.92 ± 89.30^*#	284.16 ± 184.76
3	18.99	292.2003	2,3,4-Trihydroxybutyric acid	71.89 ± 30.60	24.63 ± 24.13^*	23.02 ± 14.47^*
4	30.27	122.1582	9,12-Octadecadienoic acid	9.88 ± 5.79	24.90 ± 18.09^*#	13.57 ± 9.30
5	30.38	117.0664	Oleic acid	244.99 ± 131.32	605.66 ± 361.44^*#	346.58 ± 164.66

 ^*Compared with control group, ; ^#compared with postoperative lung cancer group, .