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BioMed Research International
Volume 2015, Article ID 183821, 7 pages
http://dx.doi.org/10.1155/2015/183821
Research Article

Determination of Serum Lost Goodwill Target Proteome in Patients with Severe Traumatic Brain Injury

1Department of Neurosurgery, Shanxi Provincial People’s Hospital, Taiyuan 030001, China
2Department of Neurosurgery, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
3Department of Neurosurgery, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430077, China
4Department of Neurosurgery, Wuhan Central Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430014, China

Received 8 March 2015; Revised 26 July 2015; Accepted 28 July 2015

Academic Editor: Aijun Wang

Copyright © 2015 Hongming Ji et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This study investigates the biokinetics of LGT proteome, a potential biomarker of severe TBI, in serum of severe TBI patients. The LGT proteome presents in the serum of severe TBI patients. The abundance diversity of LGT proteome is closely associated with pathologic condition of TBI patients. Serum LGT proteome may be used as a promising marker for evaluating severity of severe TBI.