BioMed Research International / 2015 / Article / Tab 1

Research Article

Lack of Association between Membrane-Type 1 Matrix Metalloproteinase Expression and Clinically Relevant Molecular or Morphologic Tumor Characteristics at the Leading Edge of Invasive Colorectal Carcinoma

Table 1

Clinicopathologic sample characteristics and MT1-MMP expression.

Number of patients79


Age (yrs, median/range/IQR)75/25–92/15

Tumor localization (right/left colon/unknown)27/48/4

MT1-MMP expressionMT1-MMP−MT1-MMP+P

Histopathological grading ()

UICC stage ()

T stage ()

N stage ()

KRAS mutation status ()

BRAF mutation status ()

MMR protein expression ()
 MMR proteins expressed32280.471
 Loss of MMR protein expression335

Presence of lymphovascular invasion ()

Tumor cell budding ()

Growth pattern ()

Tumor-infiltrating lymphocytes (TILs; )

1KRAS G12D, G12V, G12C, G12S, and G12R; G13D; Q61K; Q61L; 2BRAF V600E; 3MLH-1, MSH-2, MSH-6, and PMS-2; 4Chi-Square test for trend.

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