Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2015, Article ID 187620, 5 pages
http://dx.doi.org/10.1155/2015/187620
Clinical Study

Efficacy of Sublingual Immunotherapy with Dermatophagoides farinae Extract in Monosensitized and Polysensitized Patients with Allergic Rhinitis: Clinical Observation and Analysis

1Guangdong Provincial Key Laboratory of Allergy & Clinical Immunology, The State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital of Guangzhou Medical University, 250 Changgang Road East, Guangzhou 510260, China
2Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1, Shuai Fu Yuan, East District, Beijing 100730, China

Received 18 September 2014; Revised 4 February 2015; Accepted 4 February 2015

Academic Editor: Xingding Zhou

Copyright © 2015 Chen-Xia Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Bousquet, N. Khaltaev, A. A. Cruz et al., “Allergic Rhinitis and its Impact on Asthma (ARIA) 2008,” Allergy: European Journal of Allergy and Clinical Immunology, vol. 63, no. 86, pp. 8–160, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. E. P. de Groot, A. Nijkamp, E. J. Duiverman, and P. L. P. Brand, “Allergic rhinitis is associated with poor asthma control in children with asthma,” Thorax, vol. 67, no. 7, pp. 582–587, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. P.-J. Bousquet, C. Castelli, J.-P. Daures et al., “Assessment of allergen sensitization in a general population-based survey (European Community Respiratory Health Survey I),” Annals of Epidemiology, vol. 20, no. 11, pp. 797–803, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. T. J. Craig, T. S. King, R. F. Lemanske Jr. et al., “Aeroallergen sensitization correlates with PC20 and exhaled nitric oxide in subjects with mild-to-moderate asthma,” Journal of Allergy and Clinical Immunology, vol. 121, no. 3, pp. 671–677, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Didier and A. Chartier, “Specific sublingual immunotherapy: for which profiles of patients in practice? Midterm analysis of ODISSEE,” Revue Française d'Allergologie, vol. 50, no. 5, pp. 426–433, 2010. View at Google Scholar
  6. J. Li, B. Sun, Y. Huang et al., “A multicentre study assessing the prevalence of sensitizations in patients with asthma and/or rhinitis in China,” Allergy, vol. 64, no. 7, pp. 1083–1092, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. R. Mösges, E. El Hassan, and D. Passàli, “Sublingual specific immunotherapy,” Discovery Medicine, vol. 10, no. 53, pp. 348–354, 2010. View at Google Scholar · View at Scopus
  8. J. L. Brożek, J. Bousquet, C. E. Baena-Cagnani et al., “Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 Revision,” Journal of Allergy and Clinical Immunology, vol. 126, no. 3, pp. 466–476, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. Y. He, X. Liu, Y. Huang et al., “Reduction of the number of major representative allergens: from clinical testing to 3-dimensional structures,” Mediators of Inflammation, vol. 2014, Article ID 291618, 11 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. F. Horak, U. P. Stübner, R. Zieglmayer, and A. G. Harris, “Effect of desloratadine versus placebo on nasal airflow and subjective measures of nasal obstruction in subjects with grass pollen-induced allergic rhinitis in an allergen-exposure unit,” Journal of Allergy and Clinical Immunology, vol. 109, no. 6, pp. 956–961, 2002. View at Publisher · View at Google Scholar · View at Scopus
  11. K. E. Sidenius, T. E. Hallas, L. K. Poulsen, and H. Mosbech, “Allergen cross-reactivity between house-dust mites and other invertebrates,” Allergy, vol. 56, no. 8, pp. 723–733, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. H.-J. Malling, A. Montagut, M. Melac et al., “Efficacy and safety of 5-grass pollen sublingual immunotherapy tablets in patients with different clinical profiles of allergic rhinoconjunctivitis,” Clinical and Experimental Allergy, vol. 39, no. 3, pp. 387–393, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. FAO/WHO, Evaluation of Allergenicity of Genetically Modified Foods: Report of a Joint FAO/WHO Expert Consultation on Allergenicity of Foods Derived from Biotechnology, Food and Agriculture Organization of the United Nations (FAO), Rome, Italy, 2001.
  14. G. Ciprandi, G. Cadario, M. Di Gioacchino et al., “Sublingual immunotherapy in polysensitized allergic patients with rhinitis and/or asthma: allergist choices and treatment efficacy,” Journal of Biological Regulators and Homeostatic Agents, vol. 23, no. 3, pp. 165–177, 2009. View at Google Scholar · View at Scopus
  15. G. Ciprandi, G. Cadario, C. Valle et al., “Sublingual immunotherapy in polysensitized patients: effect on quality of life,” Journal of Investigational Allergology and Clinical Immunology, vol. 20, no. 4, pp. 274–279, 2010. View at Google Scholar · View at Scopus
  16. G. Ciprandi, C. Incorvaia, P. Puccinelli, S. Scurati, S. Masieri, and F. Frati, “The POLISMAIL lesson: sublingual immunotherapy may be prescribed also in polysensitized patients,” International Journal of Immunopathology and Pharmacology, vol. 23, no. 2, pp. 637–640, 2010. View at Google Scholar · View at Scopus
  17. A. Narkus, U. Lehnigk, D. Haefner, R. Klinger, O. Pfaar, and M. Worm, “The placebo effect in allergen-specific immunotherapy trials,” Clinical and Translational Allergy, vol. 3, no. 1, pp. 42–50, 2013. View at Publisher · View at Google Scholar
  18. J. Fernandes, A. Reshef, L. Patton, R. Ayuso, G. Reese, and S. B. Lehrer, “Immunoglobulin E antibody reactivity to the major shrimp allergen, tropomyosin, in unexposed Orthodox Jews,” Clinical and Experimental Allergy, vol. 33, no. 7, pp. 956–961, 2003. View at Publisher · View at Google Scholar · View at Scopus
  19. G. Reese, R. Ayuso, and S. B. Lehrer, “Tropomyosin: an invertebrate pan-allergen,” International Archives of Allergy and Immunology, vol. 119, no. 4, pp. 247–258, 1999. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Weghofer, W. R. Thomas, M. Kronqvist et al., “Variability of IgE reactivity profiles among European mite allergic patients,” European Journal of Clinical Investigation, vol. 38, no. 12, pp. 959–965, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. D.-A. Vuitton, F. Rancé, M.-L. Paquin et al., “Cross-reactivity between terrestrial snails (Helix species) and house- dust mite (Dermatophagoides pteronyssinus). I. In vivo study,” Allergy, vol. 53, no. 2, pp. 144–150, 1998. View at Publisher · View at Google Scholar · View at Scopus
  22. S. M. Satinover, A. J. Reefer, A. Pomes, M. D. Chapman, T. A. E. Platts-Mills, and J. A. Woodfolk, “Specific IgE and IgG antibody-binding patterns to recombinant cockroach allergens,” Journal of Allergy and Clinical Immunology, vol. 115, no. 4, pp. 803–809, 2005. View at Publisher · View at Google Scholar · View at Scopus
  23. Y. Resch, M. Weghofer, S. Seiberler et al., “Molecular characterization of Der p 10: a diagnostic marker for broad sensitization in house dust mite allergy,” Clinical and Experimental Allergy, vol. 41, no. 10, pp. 1468–1477, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. M. Bronnert, J. Mancini, J. Birnbaum et al., “Component-resolved diagnosis with commercially available D. pteronyssinus Der p 1, Der p 2 and Der p 10: relevant markers for house dust mite allergy,” Clinical and Experimental Allergy, vol. 42, no. 9, pp. 1406–1415, 2012. View at Publisher · View at Google Scholar · View at Scopus