Research Article

Unsaturated Fatty Acids Supplementation Reduces Blood Lead Level in Rats

Table 2

Influence of dietary supplementation with olive oil or linseed oil or super lecithin on serum lipids and lipid transfer proteins in nonpoisoned rats and rats poisoned with lead.

Group of ratsLipidsProteins
Chol
mmol/L
TG
mmol/L
HDL-C
mmol/L
HDL3-C
mmol/L
HDL2-C
mmol/L
Non
HDL-C
mmol/L
PLTP
pmol/µl/hr
CETP
pmol/µl/hr

Untreated
()
1.0 ± 0.231.04 ± 0.510.88 ± 0.230.45 ± 0.160.45 ± 0.070.62 ± 0.1470.2 ± 23.128.7 ± 3.9
Olive oil
()
1.35 ± 0.251.02 ± 0.30.95 ± 0.210.50 ± 0.120.45 ± 0.180.4 ± 0.14b82.3 ± 18.927.9 ± 5.1
Linseed oil
()
1.32 ± 0.15c0.81 ± 0.290.8 ± 0.090.52 ± 0.070.28 ± 0.07a0.53 ± 0.161.7 ± 10.931.8 ± 5.6
Super lecithin
()
1.57 ± 0.190.95 ± 0.250.95 ± 0.150.56 ± 0.10c0.39 ± 0.100.62 ± 0.2161.4 ± 11.234.4 ± 3.6b

Pb
()
1.43 ± 0.160.99 ± 0.640.93 ± 0.110.51 ± 0.060.42 ± 0.080.50 ± 0.1274.3 ± 17.729.7 ± 8.3
Pb + olive oil
()
1.42 ± 0.151.11 ± 0.460.88 ± 0.250.44 ± 0.140.44 ± 0.160.54 ± 0.285.4 ± 14.228.7 ± 2.6
Pb + linseed oil
()
1.33 ± 0.120.81 ± 0.180.87 ± 0.130.51 ± 0.070.33 ± 0.130.42 ± 0.1857.5 ± 13.627.9 ± 6.7
Pb + super lecithin
()
1.62 ± 0.261.11 ± 0.200.91 ± 0.170.57 ± 0.100.34 ± 0.100.70 ± 0.2y60.1 ± 6.8z34.1 ± 2.2

Results are presented as mean ± SD. Statistically significant differences: a, b; c in comparison to untreated rats; y, z in comparison to group of rats given lead acetate (Pb group).
Chol: cholesterol; TG: triglycerides; HDL-C: high density cholesterol; HDL3-C: HDL3 cholesterol; HDL2-C: HDL2 cholesterol; non HDL-C: non HDL cholesterol; PLTP: phospholipid transfer protein; CETP: cholesteryl ester transfer protein.