Clinical Outcomes and Urodynamic Effects of Tailored Transvaginal Mesh Surgery for Pelvic Organ Prolapse
Table 2
Changes in urodynamic variables and pad weights between baseline and after tailored anterior transvaginal mesh surgery (ATVM, = 20) or combined ATVM and tailored posterior transvaginal mesh surgery (PTVM, = 38).
Variables
ATVM
ATVM + PTVM
Baseline (a) = 20
3 months (b) = 20
12 months (c) = 9
Baseline (d) = 38
3 months (e) = 38
12 months (f) = 22
Pad weight (g)
23.7 ± 37.9
5.7 ± 14.4
10.9 ± 21.0
0.002
a versus b or c, < 0.01
32.2 ± 45.9
6.7 ± 23.8
4.4 ± 10.5
<0.001
d versus e or f, < 0.001
NDSUI
7
15
6
—
—
14
30
16
—
—
Improved
—
2
2
—
—
—
3
4
—
—
Failed
—
3
1
—
—
—
5
2
—
—
max (mL/s)
18.9 ± 11.3
19.9 ± 9.3
20.8 ± 8.6
0.83
—
21.4 ± 10.0
23.0 ± 9.6
22.0 ± 8.1
0.80
—
VV (mL)
287 ± 165
281 ± 116
267 ± 123
0.84
—
311 ± 136
306 ± 108
333 ± 151
0.56
—
PVR (mL)
42 ± 21
35 ± 14
32 ± 12
0.01
a versus b, = 0.04
57 ± 32
35 ± 14
37 ± 22
<0.001
d versus e or f, < 0.01
SD (mL)
245 ± 64
254 ± 47
262 ± 20
0.23
—
253 ± 55
266 ± 41
273 ± 36
0.08
—
Pdetmax (cmH2O)
22.5 ± 15.9
23.8 ± 13.5
27.8 ± 21.0
0.69
—
22.0 ± 11.4
32.7 ± 35.5
28.5 ± 24.1
0.22
—
MCP (cmH2O)
98.2 ± 26.7
85.2 ± 23.3
89.1 ± 27.6
0.40
—
108.1 ± 30.9
85.8 ± 22.2
85.9 ± 27.7
<0.001
d versus e or f, < 0.01
MUCP (cmH2O)
57.9 ± 24.9
41.5 ± 21.1
52.4 ± 25.4
0.007
a versus b, = 0.002
64.8 ± 27.6
41.2 ± 20.6
45.8 ± 27.0
<0.001
d versus e or f, < 0.01
FPL (cm)
2.7 ± 1.0
2.5 ± 0.7
2.4 ± 0.4
0.76
—
2.6 ± 0.6
2.4 ± 0.6
2.5 ± 0.7
0.15
—
PTR at MUP (%)
78 ± 29
95 ± 20
114 ± 40
0.002
a versus c, = 0.008
123 ± 54
102 ± 39
110 ± 26
0.08
—
DO
5
2
0
—
—
2
0
0
—
—
The values are expressed as the mean ± standard deviation or patient number. DO = detrusor overactivity; FPL = functional profile length; MUCP = maximum urethral closure pressure; NDSUI = no demonstrated SUI; Pdetmax = detrusor pressure at maximum flow rate; PTR at MUP = pressure transmission ratio at maximum urethral pressure; PVR = postvoid residual; max = maximum flow rate; SD = the volume at which a strong desire to void occurred; SUI = stress urinary incontinence; VV = voided volume. Skillings-Mack test or McNemar’s test. Post hoc test by Wilcoxon sign-rank test. Those without significant values did not show here.
