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BioMed Research International
Volume 2015, Article ID 194362, 7 pages
http://dx.doi.org/10.1155/2015/194362
Research Article

The Role and Mechanism of α-Klotho in the Calcification of Rat Aortic Vascular Smooth Muscle Cells

1Department of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
2Department of Nephrology, The First People’s Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Changzhou 213000, China

Received 16 July 2015; Revised 11 October 2015; Accepted 19 October 2015

Academic Editor: Sivagnanam Thamilselvan

Copyright © 2015 Tianlei Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [8 citations]

The following is the list of published articles that have cited the current article.

  • Rik Mencke, and Jan-Luuk Hillebrands, “The Role of the Anti-Ageing Protein Klotho in Vascular Physiology and Pathophysiology,” Ageing Research Reviews, 2016. View at Publisher · View at Google Scholar
  • Liangzhu Yu, Wei Meng, Jieqiong Ding, and Menglin Cheng, “Klotho inhibits angiotensin II-induced cardiomyocyte hypertrophy through suppression of the AT(1)R/beta catenin pathway,” Biochemical And Biophysical Research Communications, vol. 473, no. 2, pp. 455–461, 2016. View at Publisher · View at Google Scholar
  • Wei Ling Lau, Branko N. Huisa, and Mark Fisher, “The Cerebrovascular-Chronic Kidney Disease Connection: Perspectives and Mechanisms,” Translational Stroke Research, vol. 8, no. 1, pp. 67–76, 2017. View at Publisher · View at Google Scholar
  • Min Gao, Lin Wu, Xiufen Zhao, Changying Xing, Lulu Ma, and Huijuan Mao, “The suppressive effect of soluble Klotho on fibroblastic growth factor 23 synthesis in UMR-106 osteoblast-like cells,” Cell Biology International, vol. 42, no. 9, pp. 1270–1274, 2018. View at Publisher · View at Google Scholar
  • Lizhen Liao, Xiaodong Zhuang, Jie Zhao, Weidong Li, Qibiao Su, and Ying Liu, “Polysaccharide from Fuzi protects against Ox-LDL-induced calcification of human vascular smooth muscle cells by increasing autophagic activity,” Molecular Medicine Reports, vol. 17, no. 4, pp. 5109–5115, 2018. View at Publisher · View at Google Scholar
  • A. E. Khrulev, A. A. Nikitina, and N. S. Khruleva, “Specific risk factors for cerebrovascular disorders in patients with chronic kidney disease in the pre-dialysis period,” Cardiovascular Therapy and Prevention, vol. 18, no. 3, pp. 88–93, 2019. View at Publisher · View at Google Scholar
  • Jakob Voelkl, Florian Lang, Kai-Uwe Eckardt, Kerstin Amann, Makoto Kuro-o, Andreas Pasch, Burkert Pieske, and Ioana Alesutan, “Signaling pathways involved in vascular smooth muscle cell calcification during hyperphosphatemia,” Cellular and Molecular Life Sciences, 2019. View at Publisher · View at Google Scholar
  • Hsi-Ting Lin, Shao-Kuan Chen, I-Chang Su, Jiun-Wen Guo, Chi-Jung Huang, Chih-Cheng Chien, and Chih-Ju Chang, “Dynamic expression of SMAD3 is critical in osteoblast differentiation of PDMCs,” International Journal of Molecular Medicine, vol. 43, no. 2, pp. 1085–1093, 2019. View at Publisher · View at Google Scholar