Construction of a CXCL12-KDEL Fusion Gene to Inhibit Head and Neck Squamous Cell Carcinoma Metastasis by Intracellular Sequestration of CXCR4

Table 1

The expression of CXCL12/CXCR4 by IHC in different groups of patients.

Clinicopathological parameter		Positive (%)				P value
		CXCR4	CXCL12	CXCR4	CXCL12	CXCR4	CXCL12
Gender				2.694	0.756	0.101	0.384
Male	43	23 (53.5)	12 (27.9)
Female	22	12 (54.5)	6 (27.3)
Age				1.234	0.618	0.267	0.432
<60 ys	31	16 (51.6)	8 (25.8)
≥60 ys	34	19 (55.9)	10 (29.4)
Stage				16.44	0.016	0.000	0.900
I-II	26	7 (26.9)	7 (26.9)
III-IV	39	28 (71.8)	11 (28.2)
Differentiation				27.41	1.025	0.000	0.311
G1-G2	47	20 (42.6)	13 (27.7)
G3	18	15 (83.3)	5 (27.8)
Metastasis of lymph node				5.704	0.296	0.017	0.587
No	30	10 (33.3)	8 (26.7)
Yes	35	25 (71.4)	10 (28.6)