Association between Hyperhomocysteinemia and Thyroid Hormones in Euthyroid Diabetic Subjects
Table 3
Correlation with hyperhomocysteinaemia in patients with TSH < 2.5 uIU/mL.
Hyperhomocysteinaemia
Normal-homocysteine
69
124
Homocysteine (μmol/L)
21.59 ± 11.62
10.78 ± 2.41
0.000
Age (years)
57.93 ± 13.09
51.35 ± 10.43
0.000
0.003
Sex (males/females)
57/12
68/56
0.000
0.000
Duration of diabetes (years)
10.01 ± 8.62
7.08 ± 6.61
0.016
0.586
BMI (kg/m2)
25.00 ± 3.22
25.56 ± 3.98
0.318
0.393
SBP (mmHg)
134.35 ± 18.54
134.44 ± 15.56
0.972
0.747
DBP (mmHg)
80.72 ± 11.05
83.66 ± 9.37
0.052
0.131
TC (mmol/L)
4.78 ± 1.07
4.71 ± 0.97
0.634
0.334
TG (mmol/L)
2.09 ± 2.02
2.04 ± 1.36
0.842
0.518
FBG (mmol/L)
8.21 ± 3.00
9.29 ± 4.29
0.041
0.063
FT3 (pmol/L)
4.55 ± 0.62
4.49 ± 0.47
0.508
0.822
FT4 (pmol/L)
16.28 ± 2.42
16.91 ± 2.12
0.060
0.049
TSH (uIU/mL)
1.64 ± 0.47
1.61 ± 0.50
0.678
0.850
: differences between the two groups by Student’s -tests. : association with hyperhomocysteinaemia by logistic regression analyses and with homocysteine level (1 = hyperhomocysteinaemia, 0 = normal-homocysteine) as dependent variables and independent variables as follows: age, sex, BMI, duration of diabetes, BMI, SBP, DBP, TC, TG, FBG, FT3, FT4, and TSH.
