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BioMed Research International
Volume 2015, Article ID 198612, 7 pages
Review Article

An Overview of Potential Targets for Treating Amyotrophic Lateral Sclerosis and Huntington’s Disease

Laboratório de Neurofarmacologia, Departamento de Farmacologia, Instituto de Ciências Biológicas (ICB), Universidade Federal de Minas Gerais, Campus Pampulha, 31270901 Belo Horizonte, MG, Brazil

Received 5 December 2014; Accepted 8 April 2015

Academic Editor: Eduardo Candelario-Jalil

Copyright © 2015 Caroline Zocatelli de Paula et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Neurodegenerative diseases affect millions of people worldwide. Progressive damage or loss of neurons, neurodegeneration, has severe consequences on the mental and physical health of a patient. Despite all efforts by scientific community, there is currently no cure or manner to slow degeneration progression. We review some treatments that attempt to prevent the progress of some of major neurodegenerative diseases: Amyotrophic Lateral Sclerosis and Huntington’s disease.