Genome-Wide Methylome Analyses Reveal Novel Epigenetic Regulation Patterns in Schizophrenia and Bipolar Disorder

Figure 3

Ultra DMRs are associated with long CGIs and HCPs. (a) CGI length distribution for all CGIs, hypermethylated CGIs, and hypomethylated CGIs. (b) Hyper- or hypomethylated ultra DMRs are enriched in LCGI promoters ( values < 0.01, Fisher exact test). (c) The distribution of CpG ratios for aberrantly methylated promoters. (d) Hypermethylated ultra DMRs are enriched in HCPs.

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