Daycare Attendance, Breastfeeding, and the Development of Type 1 Diabetes: The Diabetes Autoimmunity Study in the Young

Table 2

Association between daycare attendance and risk of developing T1D (the Diabetes Autoimmunity Study in the Young).

Variable	Adjusted HR	95% CI	value
HLA-DR3/4, DQB1^*0302	5.06	(2.95–8.69)	<0.0001
First degree relative with T1D
Mother	1.80	(0.64–5.06)	0.27
Father or sibling	4.79	(2.60–8.84)	<0.0001
Race/ethnicity (non-Hispanic white)	1.95	(0.78–4.85)	0.15
Breastfeeding duration, months	*	*	0.38
Daycare attendance in the first 2 years	*	*	0.21
Breastfeeding duration * daycare attendance in the first 2 years of of life	*	*	0.02

The HRs and CIs of the breastfeeding duration and day care attendance in first 2 years variables were not calculated as these variables were components of the significant interaction term. The interaction between these variables is depicted in Figure 1.