[Retracted] miR-451a Inhibited Cell Proliferation and Enhanced Tamoxifen Sensitive in Breast Cancer via Macrophage Migration Inhibitory Factor

Figure 6

Effects of miR-451a and miR-451a sponge on cell survival and 4-OHT sensitivity in breast cancer cells. (a-b) MTT assay was performed to test cell survival inhibition rate in MCF-7 (a) and LCC2 (b) cells after being transfected with Lv-miR-451a or Lv-miR-451a sponge or Lv-miR-451a NC and treated with different concentrations of 4-OHT; (c) IC₅₀ value of 4-OHT was determined after cells were transfected with Lv-miR-451a or Lv-miR-451a sponge or Lv-miR-451a NC. versus Lv-miR-451a NC (MCF-7); versus Lv-miR-451a NC (LCC2) (note: NC means negative control; Lv means lentivirus).

(a)

(b)

(c)