Secretome Identifies Tenascin-X as a Potent Marker of Ovarian Cancer

Table 1

Pearson’s correlation between differentially secreted protein determined by LC-MS/MS (unique spectrum count) and circulating CA-125 in a follow-up patient study. Und = undetermined.

	A	B	C	D	Pearson’s/CA-125
MMP-2	6	25	11	16	−0.616
Vimentin	10	13	17	12	−0.670
IGF binding	15	10	13	13	0.630
Gelsolin	3	5	5	2	−0.228
Thrombospondin-1	0	5	4	2	−0.744
Complement C3	134	72	79	104	0.802
Nucleobindin 1	9	8	6	6	0.853
DKK3	4	4	4	4	Und
IGF binding	14	11	8	18	0.117
CK8	27	13	25	16	0.613
Plasminogen activator inhibitor	35	19	33	29	0.463
MMP inhibitor 2	5	6	5	5	−0.205
Collagen alpha 2 (VI) chain	0	2	0	4	−0.559
CK7	26	4	7	15	0.812
Ezrin	20	7	13	15	0.679
Aldose reductase	16	7	13	7	0.755
Retinoic acid response	10	7	6	7	0.959
Complement factor B	41	26	33	46	0.212
Complement factor I	9	8	4	7	0.655
Sulfhydryl oxidase I	22	14	18	23	0.318
Fibrillin 1	6	0	2	3	0.788
Antileukoproteinase	9	2	19	17	−0.355
Endothelial protein C receptor	4	3	0	5	0.274
Beta-1,4-Galactosyltsferase 1	5	0	5	2	0.474
Calretinin	5	4	5	2	0.531
Carboxypeptidase A4	24	5	7	14	0.828
Tenascin-X	12	4	3	2	0.999
Agrin	22	14	15	2	0.768
Superoxide dismutase	4	3	7	2	0.003
Coiled-coil domain	6	9	6	5	−0.053
UTP-glc-1P uridylyl transferase	2	2	2	0	0.432
Laminin subunit	23	23	14	18	0.612
Matrix remodeling associated	6	10	10	3	−0.137
CK19	21	13	16	9	0.849
Alpha 2 macroglobulin	10	30	41	21	−0.751
HSP10	2	0	0	0	0.990