Biphasic Regulation of Lipid Metabolism: A Meta-Analysis of Icodextrin in Peritoneal Dialysis

Table 7

Effect of icodextrin on lipid profiles in diabetes patients (in subgroups of duration).

Factor	Duration	Number of studies	Heterogeneity test				Weighted mean difference
					value	Model of meta	Mean	[95% CI]	value
Total cholesterol (mmol/L)	<6 month	2	1.06	5.60%	0.303	F			0.027
	≥6 month	2	2.05	51.20%	0.152	F			0.087
Triglycerides (mmol/L)	<6 month	2	1.63	38.60%	0.202	F			0.244
	≥6 month	2	0.49	<0.01%	0.483	F			0.467
HDL-C (mmol/L)	<6 month	2	0.17	<0.01%	0.677	F			0.845
	≥6 month	2	0.09	<0.01%	0.759	F			0.002
LDL-C (mmol/L)	<6 month	2	2.23	55.10%	0.135	F			0.057
	≥6 month	2	1.45	31.00%	0.228	F			0.171

Note: the value was less than 0.05, and the WMD was considered statistically significant.
Model of meta: F: Fixed, R: Random.