Cardiac Function in a Long-Term Follow-Up Study of Moderate and Severe Porcine Model of Chronic Myocardial Infarction

Figure 3

Echocardiography. (a)–(c) LVEF and LV volumes on echocardiography over time. (a) Left ventricular ejection fraction (LVEF) over time. (b) Left ventricular end-diastolic volume (LVEDV) over time. (c) Left ventricular end-systolic volume (LVESV) over time. (d)–(f) 3D echocardiography at 12 weeks of FU. (d) LVEF; (e) LVEDV; and (f) LVESV at 12 weeks of FU as measured by 3D echocardiography. LCx indicates left circumflex artery. LAD: left anterior descending artery. (g) Example of echocardiogram at end of systole at mid-ventricular level at 12 weeks of FU. 1 indicates a formation of scar tissue at 12 week FU. Moreover, the end-systolic diameter has been increased. (h) Example of an echocardiogram of an animal in the LCx group at 12 weeks of FU at mid-ventricular level at the end of systole. 2 indicates the location of the scar. No clear myocardial thinning could be observed in the Lcx model. .

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