Comparative Genome and Network Centrality Analysis to Identify Drug Targets of Mycobacterium tuberculosis H37Rv

Table 3

Proposed targets which interact with the host.

Protein	Functional class	Betweenness	Eigenvector	Degree	Closeness
Rv1599	Intermediary metabolism and respiration	58334.63	0.002786182	82	0.048330363
Rv1908c	Virulence, detoxification, and adaptation	50548.035	0.005637622	76	0.048456423
Rv2150c	Cell wall and cell processes	37525.4	0.007632928	103	0.048433885
Rv3921c	Cell wall and cell processes	29409.086	0.006799817	68	0.048375268
Rv0732	Cell wall and cell processes	26715.15	0.011198077	111	0.04828495
Rv1415	Intermediary metabolism and respiration	23617.264	0.002809845	57	0.048159193
Rv2534c	Information pathways	22585.9	0.010742613	123	0.04837822
Rv2553c	Cell wall and cell processes	21154.973	0.004895513	53	0.04829615
Rv1602	Intermediary metabolism and respiration	20447.479	0.002363527	49	0.048105914
Rv1611	Intermediary metabolism and respiration	17798.758	0.002891334	57	0.048196144
Rv2455c	Intermediary metabolism and respiration	16318.1045	0.00160155	54	0.04806034
Rv3601c	Intermediary metabolism and respiration	15341.172	0.00251573	49	0.048123464
Rv2538c	Intermediary metabolism and respiration	14206.7705	0.002324578	65	0.0481065
Rv2987c	Intermediary metabolism and respiration	13133.913	0.001755499	52	0.04798341
Rv1712	Intermediary metabolism and respiration	12815.694	0.002191681	62	0.048019513